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Efficacy of High-Density Three-Dimensional Mapping for Verapamil-Sensitive Left Posterior Fascicular Ventricular Tachycardia in Pediatric Patients

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Abstract

In verapamil-sensitive left posterior fascicular ventricular tachycardia (LPF-VT), radiofrequency catheter ablation (RFA) is performed targeting mid-to-late diastolic potential (P1) and presystolic potential (P2) during tachycardia. This study included four patients who had undergone electrophysiological study (EPS) and pediatric patients with verapamil-sensitive LPF-VT who had undergone RFA using high-density three-dimensional (3D) mapping. The included patients were 11–14 years old. During EPS, right bundle branch block and superior configuration VT were induced in all patients. VT mapping was performed via the transseptal approach. P1 and P2 during VT were recorded in three of the four patients. All patients initially underwent RFA via the transseptal approach. In three patients, P1 during VT was targeted, and VT was terminated. The lesion size indices in which VT was terminated were 4.6, 4.6, and 4.7. For one patient whose P1 could not be recorded, linear ablation was performed perpendicularly in the area where P2 was recorded during VT. Among the three patients in whom VT was terminated, linear ablation was performed in two to eliminate the ventricular echo beats. In all patients, VT became uninducible in the acute phase and had not recurred 8–24 months after RFA. High-density 3D mapping with an HD Grid Mapping Catheter allows recording of P1 and P2 during VT and may improve the success rate of RFA in pediatric patients with verapamil-sensitive LPF-VT.

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Acknowledgements

The authors would like to thank Enago (www.enago.jp) for the English language review.

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S.F wrote the main manuscript text. E.K, M.N, TS, YT and YY is pediatric cardiologist and carried out cardiac examination. A.C, and K.U is cardiologist and carried out EPS and RFCA with us. EK, MN, TS, YT, YY, AC, and KU critically reviewed and supervised the manuscript. All authors read and approved the final manuscript.

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Correspondence to Shuhei Fujita.

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This study was approved by our institutional ethics committee (No. 64-180), and written informed consent was obtained from the parents.

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Fujita, S., Kabata, E., Nishiyama, M. et al. Efficacy of High-Density Three-Dimensional Mapping for Verapamil-Sensitive Left Posterior Fascicular Ventricular Tachycardia in Pediatric Patients. Pediatr Cardiol 45, 368–376 (2024). https://doi.org/10.1007/s00246-023-03352-1

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