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Lactate biosensors: current status and outlook

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Abstract

Many research efforts over the last few decades have been devoted to sensing lactate as an important analytical target in clinical care, sport medicine, and food processing. Therefore, research in designing lactate sensors is no longer in its infancy and now is more directed toward viable sensors for direct applications. In this review, we provide an overview of the most immediate and relevant developments toward this end, and we discuss and assess common transduction approaches. Further, we critically describe the pros and cons of current commercial lactate sensors and envision how future sensing design may benefit from emerging new technologies.

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Authors and Affiliations

  1. Laboratory of Organic Materials and Interfaces, Department of Chemical Engineering, Delft University of Technology, Julianalaan 136, 2628, BL, Delft, The Netherlands

    Liza Rassaei & Ernst J. R. Sudhölter

  2. MESA + Institute, BIOS/Lab-on-a-Chip group, University of Twente, PO Box 217, 7500, Enschede, The Netherlands

    Wouter Olthuis & Albert van den Berg

  3. Division of Materials Science, Faculty of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8573, Japan

    Seiya Tsujimura

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  1. Liza Rassaei
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  2. Wouter Olthuis
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  3. Seiya Tsujimura
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  4. Ernst J. R. Sudhölter
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Correspondence to Liza Rassaei.

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Rassaei, L., Olthuis, W., Tsujimura, S. et al. Lactate biosensors: current status and outlook. Anal Bioanal Chem 406, 123–137 (2014). https://doi.org/10.1007/s00216-013-7307-1

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  • DOI: https://doi.org/10.1007/s00216-013-7307-1

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