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Occurrence of Veterinary Antibiotics in Swine Manure from Large-scale Feedlots in Zhejiang Province, China

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Abstract

The occurrence and distribution of five sulfonamides and three tetracyclines in swine manure sampled from large-scale feedlots in different areas of Zhejiang Province, China were detected using solid-phase extraction and high-performance liquid chromatography. All eight test antibiotics were detected in most of the manure samples. The dominant antibiotics in swine manure were sulfadiazine, sulfamerazine, sulfadimidine, tetracycline, and chlortetracycline. The maximum concentration of residual antibiotic reached up to 57.95 mg/kg (chlortetracycline). The concentrations and distribution of both types of antibiotics in swine manure of different areas varied greatly. Relatively higher concentrations of sulfonamides were found in swine manure from the Zhejiang area in this experiment compared with previous studies. The results revealed that antibiotics were extensively used in feedlots in this district and that animal manure might act as a non-specific source of antibiotic residues in farmlands and aquatic environments.

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Acknowledgements

This work was funded by the Innovative Team Foundation of Zhejiang Province (2013TD12), International Science and Technology Cooperation Program of China (2014DFE90040), and the Significant Science and Technology Project of Zhejiang Province (2015C33006).

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Correspondence to Chengran Fang.

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Wang, H., Chu, Y. & Fang, C. Occurrence of Veterinary Antibiotics in Swine Manure from Large-scale Feedlots in Zhejiang Province, China. Bull Environ Contam Toxicol 98, 472–477 (2017). https://doi.org/10.1007/s00128-017-2052-3

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  • DOI: https://doi.org/10.1007/s00128-017-2052-3

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