Abstract
Background
Similar to the US, mortality due to suicide and the use of opioids, alcohol, and other substances (so-called “Deaths of Despair”), is rising in Canada and has been disproportionately observed among Whites compared to other racial and ethnic groups. This study aimed to assess the determinants of the ethno-racial differences in the use of substances that underlie these deaths.
Methods
Using nationally representative data from the Canadian Community Health Survey (2003, 2015–2016, 2018 cycles), a decomposition analysis was performed to estimate the contribution of psychosocial determinants, including age, sex, marital status, immigration, education, income, rurality, and affective health on inequalities between White and non-White populations in illicit substance, opioid, and problematic alcohol use and combined use (≥ 2) of substances.
Results
Overall, White respondents reported higher levels (by 5% to 10%) of substance use than non-White peers. Over 30% of the ethno-racial inequalities in illicit substance, problematic alcohol, and polysubstance use are explained by the protective role of immigration among those who are not White, whose low levels of substance use lower the prevalence in the non-White population overall. Among those born in Canada, no ethno-racial differences in substance use were observed.
Conclusion
Social determinants, particularly immigrant status, explain a substantial proportion of ethno-racial inequalities in substance use in Canada. The jump in substance use between racialized populations who immigrated to Canada and those Canadian-born highlights the importance of exploring within-group variability in deaths of despair risk and considering how intersecting forces including systemic racism shape substance use patterns across generations.
Similar content being viewed by others
Availability of data and code
Data are owned and protected by Statistics Canada and cannot be released.
References
Peacock A, Leung J, Larney S, Colledge S, Hickman M, Rehm J et al (2018) Global statistics on alcohol, tobacco and illicit drug use: 2017 status report. Addiction 113(10):1905–1926
European Monitoring Centre for Drugs and Drug Addiction (2019) European drug report: trends and developments. Office of the European Union, Lisbon. Available from: https://www.emcdda.europa.eu/publications/edr/trends-developments/2019_en. Accessed 23 Feb 2022
Karanges EA, Blanch B, Buckley NA, Pearson SA (2016) Twenty-five years of prescription opioid use in Australia: a whole-of-population analysis using pharmaceutical claims. J Br J Clin Pharmacol 82(1):255–267
Roxburgh A, Hall WD, Dobbins T, Gisev N, Burns L, Pearson S et al (2017) Trends in heroin and pharmaceutical opioid overdose deaths in Australia. Drug Alcohol Depend 179:291–298
Case A, Deaton A (2017) Mortality and morbidity in the 21st century. Brook Pap Econ Act 2017(1):397–476
McKernan S-M, Ratcliffe C, Steuerle CE, Kalish E, Quakenbush C, Lei S, et al. (2015) Nine charts about wealth inequality in America. Washington, DC: Urban Institute. Availabe from: https://apps.urban.org/features/wealth-inequality-charts. Accessed 23 Feb 2022
Hamilton D, Darity W Jr, Price AE, Sridharan V, Tippett R (2015) Umbrellas don’t make it rain: Why studying and working hard isn’t enough for Black Americans. New York: The New School 779:780–781
Gordon A (2005) The creation of homeownership: how new deal changes in banking regulation simultaneously made homeownership accessible to whites and out of reach for blacks. Yale LJ 115:186
Siddiqi A, Sod-Erdene O, Hamilton D, Cottom TM, Darity W (2019) Growing sense of social status threat and concomitant deaths of despair among whites. SSM - Popul Health 9:100449
Jones SC, Brooks JH, Milam AJ, Barajas CB, LaVeist TA, Kane E et al (2019) Racial discrimination, John Henryism coping, and behavioral health conditions among predominantly poor, urban African Americans: implications for community-level opioid problems and mental health services. J Community Psychol 47(5):1032–1042
Billings AG, Moos RH (1981) The role of coping responses and social resources in attenuating the stress of life events. J Behav Med 4(2):139–157
Fischer B, Cruz MF, Rehm J (2006) Illicit opioid use and its key characteristics: a select overview and evidence from a Canadian multisite cohort of illicit opioid users (OPICAN). Can J Psychiatry 51(10):624–634
Skinner R, McFaull S, Rhodes AE, Bowes M, Rockett IRH (2016) Suicide in Canada: Is poisoning misclassification an Issue? Can J Psychiatry 61(7):405–412
Jackson JW, Williams DR, VanderWeele TJ (2016) Disparities at the intersection of marginalized groups. Soc Psychiatry Psychiatr Epidemiol 51(10):1349–1359
Khalid M (2019) Unpacking Canadian deaths of despair. Can Issues. 43:8
Fischer B (2015) Prescription opioid use, harms and interventions in Canada: a review update of new developments and findings since 2010. Pain Physician 18:E605–E614
Public Health Agency of Canada (PHAC) (2019) National report: Opioid-related Harms in Canada. Ottawa, Canada. Available from: https://www.canada.ca/en/health-canada/services/opioids/data-surveillance-research.html. Accessed 29 Oct 2020
Canadian Institute for Health Information (2018) Opioid-related harms in Canada. Ottawa, Canada. Availabe from: https://www.cihi.ca/sites/default/files/document/opioid-related-harms-report-2018-en-web.pdf. Accessed 23 Feb 2022
Centers for Disease Control and Prevention (CDC) (2021) Opioid basics: Understanding the Epidemic. Atlanta, Georgia. Availabe from: https://www.cdc.gov/opioids/basics/epidemic.html. Accessed 23 Feb 2022
Belzak L, Halverson J (2018) The opioid crisis in Canada: a national perspective. Health Promot Chronic Dis Prev Can 38(6):224–233
McKeown D (2015) Staff report for action on overdose in Toronto: trends, prevention and response Toronto, Canada. Available from: https://www.toronto.ca/legdocs/mmis/2015/hl/bgrd/backgroundfile-83429.pdf. Accessed 23 Feb 2022
Public Health Agency of Canada (2021) Opioid- and stimulant-related harms in Canada. Ottawa, Canada. Available from: https://health-infobase.canada.ca/substance-related-harms/opioids-stimulants/graphs?index=2507. Accessed 23 Feb 2022
Gomes T, Pasricha S, Martins D, Greaves S, Tadrous M, Bandola D (2017) Behind the prescriptions a snapshot of opioid use across all Ontarians. Ontario Drug Policy Research Network, Toronto. Available from: https://odprn.ca/research/publications/opioid-prescribing-in-ontario-august-2017/. Accessed 23 Feb 2022
Smolina K, Gladstone E, Morgan SG (2016) Determinants of trends in prescription opioid use in British Columbia, Canada, 2005–2013. Pharmacoepidemiol Drug Saf 25(5):553–559
Archie S, Zangeneh Kazemi A, Akhtar-Danesh N (2012) Concurrent binge drinking and depression among Canadian youth: prevalence, patterns, and suicidality. Alcohol 46(2):165–172
Holligan SD, Qian W, de Groh M, Jiang Y, Leatherdale ST (2020) Micro-level factors associated with alcohol use and binge drinking among youth in the COMPASS study (2012/13 to 2017/18). Health Promot Chronic Dis Prev Can 40(3):63–69
Knerich V, Jones AA, Seyedin S, Siu C, Dinh L, Mostafavi S et al (2019) Social and structural factors associated with substance use within the support network of adults living in precarious housing in a socially marginalized neighborhood of Vancouver. Canada. PloS one 14(9):0222611
Goldman-Hasbun J, Nosova E, Kerr T, Wood E, DeBeck K (2019) Homelessness and incarceration associated with relapse into stimulant and opioid use among youth who are street-involved in Vancouver. Can Drug Alcohol Rev 38(4):428–434
Statistics Canada (2003) Canadian Community Health Survey (CCHS) Cycle 2.1 (2003) Public use microdata file documentation. Ottawa, Canada. Available from: https://www23.statcan.gc.ca/imdb/p2SV.pl?Function=getSurvey&Id=4995. Accessed 29 Oct 2020
Statistics Canada (2017) Canadian Community Health Survey—Nutrition (CCHS): Data accuracy. Ottawa, Canada. Availabe from: https://www23.statcan.gc.ca/imdb/p2SV.pl?Function=getSurvey&SDDS=5049. Accessed 23 Feb 2022
Statistics Canada (2019) Canadian Community Health Survey (CCHS) Annual component: User guide—2018 and 2017-2018 Microdata file. Ottawa, Canda. Availabe from: http://odesi1.scholarsportal.info/documentation/CCHS_2017-2018/CCHS2017-2018UserGuide.pdf. Accessed 23 Feb 2022
Statistics Canada (2018) Canadian Community Health Survey—Annual component (CCHS). Ottawa, Canada. Availabe from: https://www23.statcan.gc.ca/imdb/p2SV.pl?Function=getSurvey&Id=795204. Accessed 23 Feb 2022
Statistics Canada (2017) Methodology of the Canadian Labour Force Survey: Chapter 3 Dwelling frame creation and maintenance Ottawa, Canada: Government of Canada. Available from: https://www150.statcan.gc.ca/n1/pub/71-526-x/2017001/chapt3-eng.htm. Accessed 23 Feb 2022
Statistics Canada (2016) Canadian Community Health Survey (CCHS)—2015 questionnaire Ottawa, Canada: statistics Canada. Available from: https://www23.statcan.gc.ca/imdb/p3Instr.pl?Function=assembleInstr&a=1&&lang=en&Item_Id=238890. Accessed 23 Feb 2022
Butt P, Beirness D, Gliksman L, Paradis C, Stockwell T (2011) Alcohol and health in Canada: a summary of evidence and guidelines for low-risk drinking. Canadian Centre on Substance Abuse, Ottawa, ON. Available from: https://www.camh.ca/-/media/files/canadas-low-risk-guidelines-pdf.pdf. Accessed 23 Mar 2022
Klimas J, Gorfinkel L, Fairbairn N, Amato L, Ahamad K, Nolan S et al (2019) Strategies to identify patient risks of prescription opioid addiction when initiating opioids for pain: a systematic review. JAMA Netw Open 2(5):193365
Minozzi S, Amato L, Davoli M (2013) Development of dependence following treatment with opioid analgesics for pain relief: a systematic review. Addiction 108(4):688–698. https://doi.org/10.1111/j.1360-0443.2012.04005.x
Voon P, Karamouzian M, Kerr T (2017) Chronic pain and opioid misuse: a review of reviews. Subst Abuse Treat Prev Policy 12(1):36
Ray JG, Hollands S, Gomes T, Urquia ML, Macdonald EM, Li P et al (2014) Risk of overdose and death following codeine prescription among immigrants. J Epidemiol Community Health 68(11):1057
Harvard School of Public Health (2021) The Public Health Disparities Geocoding Project Monograph Analytic Methods. The Public Health Disparities Geocoding Project. Boston, USA. Available from https://www.hsph.harvard.edu/thegeocodingproject/analytic-methods/. Accessed 15 June 2021
Blinder AS (1973) Wage discrimination: reduced form and structural estimates. J Human Res 8(4):36–55
Oaxaca R (1973) Male-female wage differentials in urban labor markets. Int Econ Rev 14(3):693–709
Powers DA, Yoshioka H, Yun M-S (2011) Mvdcmp: Multivariate decomposition for nonlinear response models. Stand Genomic Sci 11(4):556–576
StataCorp (2019) Stata Statistical Software: Release 16. StataCorp LLC, College Station, TX
Card KG, Fournier AB, Sorge JT, Morgan J, Grace D, Ham D et al (2020) Substance use patterns and awareness of biomedical HIV prevention strategies among sexual and gender minority men in Canada. AIDS Care 32(12):1506–1514
Shokoohi M, Bauer GR, Kaida A, Logie CH, Lacombe-Duncan A, Milloy MJ et al (2019) Patterns of social determinants of health associated with drug use among women living with HIV in Canada: a latent class analysis. Addiction 114(7):1214–1224
Lake S, Kerr T, Buxton J, Guillemi S, Parashar S, Montaner J et al (2016) Prescription Opioid Injection Among HIV-Positive People Who Inject Drugs in a Canadian Setting. AIDS Behav 20(12):2941–2949
Roy É, Richer I, Arruda N, Vandermeerschen J, Bruneau J (2013) Patterns of cocaine and opioid co-use and polyroutes of administration among street-based cocaine users in Montréal, Canada. Int J Drug Policy 24(2):142–149
Lloyd-Smith E, Wood E, Li K, Montaner JSG, Kerr T (2009) Incidence and determinants of initiation into cocaine injection and correlates of frequent cocaine injectors. Drug Alcohol Depend 99(1):176–182
Ahamad K, Milloy MJ, Nguyen P, Uhlmann S, Johnson C, Korthuis TP et al (2015) Factors associated with willingness to take extended release naltrexone among injection drug users. Addict Sci Clin Pract 10:12
Tucker D, Milloy MJ, Hayashi K, Nguyen P, Kerr T, Wood E (2015) Factors associated with illicit methadone injecting in a Canadian setting. Am J Addict 24(6):532–537
Shaw SY, Shah L, Jolly AM, Wylie JL (2008) Identifying heterogeneity among injection drug users: a cluster analysis approach. Am J Public Health 98(8):1430–1437
Fairbairn N, Kerr T, Buxton JA, Li K, Montaner JS, Wood E (2007) Increasing use and associated harms of crystal methamphetamine injection in a Canadian setting. Drug Alcohol Depend 88(2–3):313–316
Abuelezam NN, El-Sayed AM, Galea S (2019) Differences in health behaviors and health outcomes among non-hispanic whites and Arab Americans in a population-based survey in California. BMC Pub Health 19(1):892
Arfken CL, Arnetz BB, Fakhouri M, Ventimiglia MJ, Jamil H (2011) Alcohol use among Arab Americans: what is the prevalence? J Immigr Minor Health 13(4):713–718
Areba EM, Watts AW, Larson N, Eisenberg ME, Neumark-Sztainer D (2021) Acculturation and ethnic group differences in well-being among Somali, Latino, and Hmong adolescents. Am J Orthopsychiatry 91(1):109–119
Centers for Disease Control and Prevention (CDC) (2017) Table 0.50: Use of selected substances in the past month among persons aged 12 and over, by age, sex, race, and Hispanic origin: United States, selected years 2002–2016. Atlanta, USA. Available from: https://www.cdc.gov/nchs/hus/contents2017.htm#050. Accessed 23 Feb 2022
Agic B, Mann RE, Kobus-Matthews M (2011) Alcohol use in seven ethnic communities in Ontario: a qualitative investigation. Drugs Educt, Prev Policy 18(2):116–123
Szaflarski M, Klepinger DH, Cubbins LA (2019) Alcohol use/abuse and help-seeking among US adults: the role of racial-ethnic origin and foreign-born status. J Ethnicity Subst Abus 18(2):183–210
Amundsen EJ (2012) Low level of alcohol drinking among two generations of non-western immigrants in oslo: a multi-ethnic comparison. BMC Pub Health 12:535
Reijneveld SA, van Nieuwenhuijzen M, Klein Velderman M, Paulussen TW, Junger M (2012) Clustering of health and risk behaviour in immigrant and indigenous Dutch residents aged 19–40 years. Int J Public Health 57(2):351–361
Khlat M, Legleye S, Bricard D (2020) Gender patterns in immigrants’ health profiles in France: tobacco, alcohol, obesity and self-reported health. Int J Environ Res Pub Health 17(23):8759
Borges G, Cherpitel CJ, Orozco R, Zemore SE, Wallisch L, Medina-Mora ME et al (2016) Substance use and cumulative exposure to American society: findings from both sides of the US-Mexico border region. Am J Pub Health 106(1):119–127
Salas-Wright CP, Vaughn MG, Clark TT, Terzis LD, Córdova D (2014) Substance use disorders among first- and second- generation immigrant adults in the United States: evidence of an immigrant paradox? J Stud Alcohol Drugs 75(6):958–967
Aldridge-Gerry AA, Roesch SC, Villodas F, McCabe C, Leung QK, Da Costa M (2011) Daily stress and alcohol consumption: modeling between-person and within-person ethnic variation in coping behavior. J Stud Alcohol Drugs 72(1):125–134
Mezuk B, Abdou CM, Hudson D, Kershaw KN, Rafferty JA, Lee H et al (2013) White Box. The Environmental Affordances Model. Soc Ment Health, Epidemiology and the Social Neuroscience of Health Behaviors. https://doi.org/10.1177/2156869313480892
Caetano R, Clark CL, Tam T (1998) Alcohol consumption among racial/ethnic minorities: theory and research. Alcohol Health Res World 22(4):233–241
Ali J. (2020) Mental health of Canada’s immigrants. Supplement to Statistics Canada Health Reports. Ottawa, Canada. Available from: https://www150.statcan.gc.ca/n1/en/catalogue/82-003-S20020016336. Accessed 23 Feb 2022
MacDonald J (2006) The health behaviours of immigrants and native-born people in Canada. 1–41. Working paper available at http://community.smu.ca/atlantic/documents/McDonald-WP1.pdf. Accessed 23 Feb 2022
Acevedo-Garcia D, Sanchez-Vaznaugh EV, Viruell-Fuentes EA, Almeida J (2012) Integrating social epidemiology into immigrant health research: a cross-national framework. Soc Sci Med 75(12):2060–2068
Salas-Wright CP, Vaughn MG (2014) A “refugee paradox” for substance use disorders? Drug Alcohol Depend 142:345–349
Cardoso JB, Goldbach JT, Cervantes RC, Swank P (2016) Stress and multiple substance use behaviors among hispanic adolescents. Prev Sci: Off J Soc Prev Res 17(2):208–217
Conn BM, Ejesi K, Foster DW (2017) Acculturative stress as a moderator of the effect of drinking motives on alcohol use and problems among young adults. Addict Behav 75:85–94
Blanco C, Morcillo C, Alegría M, Dedios MC, Fernández-Navarro P, Regincos R et al (2013) Acculturation and drug use disorders among hispanics in the US. J Psychiatr Res 47(2):226–232
Weiss NH, Johnson CD, Contractor A, Peasant C, Swan SC, Sullivan TP (2017) Racial/ethnic differences moderate associations of coping strategies and posttraumatic stress disorder symptom clusters among women experiencing partner violence: a multigroup path analysis. Anxiety Stress Coping 30(3):347–363
Souleymanov R, Brennan DJ, George C, Utama R, Ceranto A (2020) Experiences of racism, sexual objectification and alcohol use among gay and bisexual men of colour. Ethn Health 25(4):525–541
Cano M, Sánchez M, Trepka MJ, Dillon FR, Sheehan DM, Rojas P et al (2017) Immigration stress and alcohol use severity among recently immigrated hispanic adults: examining moderating effects of gender, immigration status, and social support. J Clin Psychol 73(3):294–307
Cook WK, Bond J, Karriker-Jaffe KJ, Zemore S (2013) Who’s at risk? Ethnic drinking cultures, foreign nativity, and problem drinking among Asian American young adults. J Stud Alcohol Drugs 74(4):532–541
Carliner H, Delker E, Fink DS, Keyes KM, Hasin DS (2016) Racial discrimination, socioeconomic position, and illicit drug use among US blacks. Soc Psychiatry Psychiatr Epidemiol 51(4):551–560
Solar O, Irwin A (2010) A conceptual framework for action on the social determinants of health Social Determinants of Health, Discussion Paper 2. World Health Organization, Geneva: p.1-76. Available from: https://apps.who.int/iris/handle/10665/44489. Accessed 23 Feb 2022
Hankivsky O, Christoffersen A (2008) Intersectionality and the determinants of health: a Canadian perspective. Crit Pub Health 18(3):271–283
Hoertel N, Franco S, Wall MM, Oquendo MA, Kerridge BT, Limosin F et al (2015) Mental disorders and risk of suicide attempt: a national prospective study. Mol Psychiatry 20(6):718–726
Saddichha S, Werker GR, Schuetz C, Krausz MR (2015) Stimulants and cannabis use among a marginalized population in British Columbia, Canada: role of trauma and incarceration. Int J Offender Ther Comp Criminol 59(13):1487–1498
Tucker D, Hayashi K, Milloy MJ, Nolan S, Dong H, Kerr T et al (2016) Risk factors associated with benzodiazepine use among people who inject drugs in an urban Canadian setting. Addict Behav 52:103–107
Boyd J, Fast D, Hobbins M, McNeil R, Small W (2017) Social-structural factors influencing periods of injection cessation among marginalized youth who inject drugs in Vancouver, Canada: an ethno-epidemiological study. Harm Reduct J 14(1):31
Wood E, Spittal PM, Small W, Kerr T, Li K, Hogg RS et al (2004) Displacement of Canada’s largest public illicit drug market in response to a police crackdown. Can Med Assoc J 170(10):1551–1556
Acknowledgements
We would like to thank Z. Zhao for his logistical support for this project. Although the research and analysis are based on data from Statistics Canada, the opinions expressed do not represent the views of Statistics Canada. Note that throughout this study, the term “White” was applied with uppercase lettering, as a proper noun, in acknowledgement of the construction of Whiteness as a racial identity.
Funding
This work was supported by the Fonds de Recherche du Québec–Santé [Postdoctoral Fellowship] and the Canadian Institutes of Health Research [Canada Research Chair in Health Equity].
Author information
Authors and Affiliations
Contributions
AB–developed the study design, conducted analyses, drafted and reviewed the manuscript. AS–developed the study design, drafted and reviewed the manuscript.
Corresponding author
Ethics declarations
Conflict of interest
The authors declare that they have no conflict of interest.
Ethical approval
The project was approved by, and data were accessed through and analyzed at, the University of Toronto Research Data Center. Ethics approval was not applicable, as the University of Toronto does not require ethics review for secondary data analysis using Statistics Canada data.
Supplementary Information
Below is the link to the electronic supplementary material.
Rights and permissions
About this article
Cite this article
Blair, A., Siddiqi, A. Social determinants of ethno-racial inequalities in substance use: a decomposition of national survey data. Soc Psychiatry Psychiatr Epidemiol 57, 2013–2022 (2022). https://doi.org/10.1007/s00127-022-02281-3
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00127-022-02281-3