Skip to main content
Log in

Dual-source-CT in der Diagnostik des Thoraxschmerzes

Dual-source CT in chest pain diagnosis

  • Leitthema
  • Published:
Der Radiologe Aims and scope Submit manuscript

Zusammenfassung

Hintergrund

Die EKG-getriggerte CT-Angiographie kann mit der Darstellung von Koronar-, Lungenarterien und Aorta eine umfassende Abklärung des unklaren Thoraxschmerzes leisten. Ziel unserer Untersuchungen war es, die diagnostische Wertigkeit des Dual-source-CT in diesem Patientenkollektiv festzustellen.

Material und Methodik

47 Patienten mit unklarem Thoraxschmerz wurden an einem Siemens Somatom Definition untersucht. Menge und Injektionsgeschwindigkeit des Kontrastmittels (Ultravist, Schering) wurden auf das Körpergewicht adaptiert. Die Untersuchungen wurden hinsichtlich der Bildqualität und Kontrastierung sowie der diagnostischen Genauigkeit im Vergleich zur endgültigen klinischen Diagnose beurteilt.

Ergebnisse

Bei allen Untersuchungen wurde eine ausreichende Kontrastierung erzielt. Die Darstellung der Koronararterien war in allen Fällen diagnostisch. Die Ursache des Thoraxschmerzes konnte bei 41 Patienten identifiziert werden. Das Diagnosenspektrum umfasste koronare und myokardiale Ursachen, Klappenfehler, Aortenaneurysmata und Dissektionen, Lungenembolien und pneumonische Infiltrate.

Schlussfolgerung

Die Thoraxangiographie am DSCT bietet auch bei hohen Herzfrequenzen eine sehr gute Bildqualität, sodass auch bei akutem Thoraxschmerz eine hohe diagnostische Aussagekraft gewährleistet ist.

Abstract

Background

With the depiction of pulmonary arteries, coronary arteries, and the aorta, CT angiography of the chest offers a comprehensive diagnostic work-up of unclear chest pain. The aim of this study was to assess the diagnostic accuracy of dual-source CT in this patient group.

Materials and methods

A total of 47 patients suffering from unclear chest pain were examined with a Siemens Somatom Definition. Volume and flow of contrast media (Ultravist, Schering) were adapted to the body weight. The examinations were evaluated with regard to image quality and contrast opacification and to the diagnostic accuracy with reference to the final clinical diagnosis.

Results

Adequate contrast opacification was achieved in all examinations. The depiction of the coronary arteries was diagnostic in all cases. The cause of chest pain could be identified in 41 cases. Among the diagnoses were coronary and myocardial pathologies, valvular disease, aortic aneurysms and dissections, pulmonary embolism, and pneumonic consolidation.

Conclusion

DSCT angiography of the chest offers a very good image quality even at high heart rates so that a high diagnostic accuracy is achieved in patients with acute chest pain.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Abb. 1
Abb. 2
Abb. 3
Abb. 4
Abb. 5

Literatur

  1. American College of Emergency Physicians (1995) Clinical policy for the initial approach to adults presenting with a chief complaint of chest pain, with no history of trauma. Ann Emerg Med 25: 274–299

    Article  PubMed  Google Scholar 

  2. Erhardt L, Herlitz J, Bossaert L et al. (2002) Task force on the management of chest pain. Eur Heart J 23: 1153–1176

    Article  PubMed  Google Scholar 

  3. Hamm CW (2004) Guidelines: acute coronary syndrome (ACS). 1. ACS without persistent ST segment elevations. Z Kardiol 93: 72–90

    Article  PubMed  Google Scholar 

  4. Lee TH, Cook EF, Weisberg M et al. (1985) Acute chest pain in the emergency room. Identification and examination of low-risk patients. Arch Intern Med 145: 65–69

    Article  PubMed  Google Scholar 

  5. Solomon CG, Lee TH, Cook EF et al. (1989) Comparison of clinical presentation of acute myocardial infarction in patients older than 65 years of age to younger patients: the Multicenter Chest Pain Study experience. Am J Cardiol 63: 772–776

    Article  PubMed  Google Scholar 

  6. Lee TH, Goldman L (2000) Evaluation of the patient with acute chest pain. N Engl J Med 342: 1187–1195

    Article  PubMed  Google Scholar 

  7. Achenbach S, Giesler T, Ropers D et al. (2001) Detection of coronary artery stenoses by contrast-enhanced, retrospectively electrocardiographically-gated, multislice spiral computed tomography. Circulation 103: 2535–2538

    PubMed  Google Scholar 

  8. Nieman K, Oudkerk M, Rensing BJ et al. (2001) Coronary angiography with multislice computed tomography. Lancet 357: 599–603

    Article  PubMed  Google Scholar 

  9. Knez A, Becker CR, Leber A et al. (2001) Usefulness of multislice spiral computed tomography angiography for determination of coronary artery stenoses. Am J Cardiol 88: 1191–1194

    Article  PubMed  Google Scholar 

  10. White CS, Kuo D, Kelemen M et al. (2005) Chest pain evaluation in the emergency department: can MDCT provide a comprehensive evaluation? AJR Am J Roentgenol 185: 533–540

    PubMed  Google Scholar 

  11. Sato Y, Matsumoto N, Ichikawa M et al. (2005) Efficacy of multislice computed tomography for the detection of acute coronary syndrome in the emergency department. Circ J 69: 1047–1051

    Article  PubMed  Google Scholar 

  12. Johnson TRC, Nikolaou K, Wintersperger BJ et al. (2006) Optimization of contrast material administration for electrocardiogram-gated computed tomographic angiography of the chest. J Comput Assist Tomogr 30: ■

  13. Johnson TRC, Nikolaou K, Wintersperger BJ et al. (2007) ECG gated 64 slice CT angiography for the differential diagnosis of acute chest pain. AJR Am J Roentgenol 188: ■

  14. Johnson TR, Nikolaou K, Wintersperger BJ et al. (2006) Dual-source CT cardiac imaging: initial experience. Eur Radiol 16: 1409–1415

    Article  PubMed  Google Scholar 

  15. Scheffel H, Alkadhi H, Plass A et al. (2006) Accuracy of dual-source CT coronary angiography: first experience in a high pre-test probability population without heart rate control. Eur Radiol ■: ■

  16. Achenbach S, Ropers D, Kuettner A et al. (2006) Contrast-enhanced coronary artery visualization by dual-source computed tomography – initial experience. Eur J Radiol 57: 331–335

    Article  PubMed  Google Scholar 

  17. Chambers J, Bass C, Mayou R (1999) Non-cardiac chest pain: assessment and management. Heart 82: 656–657

    PubMed  Google Scholar 

  18. Fruergaard P, Launbjerg J, Hesse B et al. (1996) The diagnoses of patients admitted with acute chest pain but without myocardial infarction. Eur Heart J 17: 1028–1034

    PubMed  Google Scholar 

  19. Lee TH, Rouan GW, Weisberg MC et al. (1987) Sensitivity of routine clinical criteria for diagnosing myocardial infarction within 24 hours of hospitalization. Ann Intern Med 106: 181–186

    PubMed  Google Scholar 

  20. Weissman IA, Dickinson CZ, Dworkin HJ et al. (1996) Cost-effectiveness of myocardial perfusion imaging with SPECT in the emergency department evaluation of patients with unexplained chest pain. Radiology 199: 353–357

    PubMed  Google Scholar 

  21. Trippi JA, Lee KS, Kopp G et al. (1997) Dobutamine stress tele-echocardiography for evaluation of emergency department patients with chest pain. J Am Coll Cardiol 30: 627–632

    Article  PubMed  Google Scholar 

  22. Thoongsuwan N, Stern ET (2002) Chest CT scanning for clinical suspected thoracic aortic dissection: beware the alternate diagnosis. Emerg Radiol 9: 257–261

    PubMed  Google Scholar 

  23. Fossum E, Ata B, Eritsland J et al. (2003) Aortic dissection a differential diagnosis in patients with chest pain and ECG changes. Tidsskr Nor Laegeforen 123: 2430–2432

    PubMed  Google Scholar 

  24. Watanabe T, Kikushima S, Tanno K et al. (1998) Uncommon electrocardiographic changes corresponding to symptoms during recurrent pulmonary embolism as documented by computed tomography scans. Clin Cardiol 21: 858–861

    PubMed  Google Scholar 

  25. O’Neill J, Murchison JT, Wright L, Williams J (2005) Effect of the introduction of helical CT on radiation dose in the investigation of pulmonary embolism. Br J Radiol 78: 46–50

    Article  PubMed  Google Scholar 

  26. Marten K, Engelke C, Funke M et al. (2003) ECG-gated multislice spiral CT for diagnosis of acute pulmonary embolism. Clin Radiol 58: 862–868

    Article  PubMed  Google Scholar 

  27. Roos JE, Willmann JK, Weishaupt D et al. (2002) Thoracic aorta: motion artifact reduction with retrospective and prospective electrocardiography-assisted multi-detector row CT. Radiology 222: 271–277

    PubMed  Google Scholar 

  28. Schoepf UJ, Becker CR, Ohnesorge BM, Yucel EK (2004) CT of coronary artery disease. Radiology 232: 18–37

    PubMed  Google Scholar 

  29. Leung KC, Martin CJ (1996) Effective doses for coronary angiography. Br J Radiol 69: 426–431

    PubMed  Google Scholar 

  30. Ghaye B, Remy J, Remy-Jardin M (2002) Non-traumatic thoracic emergencies: CT diagnosis of acute pulmonary embolism: the first 10 years. Eur Radiol 12: 1886–1905

    PubMed  Google Scholar 

  31. Remy-Jardin M, Remy J, Deschildre F et al. (1996) Diagnosis of pulmonary embolism with spiral CT: comparison with pulmonary angiography and scintigraphy. Radiology 200: 699–706

    PubMed  Google Scholar 

  32. Qanadli SD, Hajjam ME, Mesurolle B et al. (2000) Pulmonary embolism detection: prospective evaluation of dual-section helical CT versus selective pulmonary arteriography in 157 patients. Radiology 217: 447–455

    PubMed  Google Scholar 

  33. Garg K, Welsh CH, Feyerabend AJ et al. (1998) Pulmonary embolism: diagnosis with spiral CT and ventilation-perfusion scanning – correlation with pulmonary angiographic results or clinical outcome. Radiology 208: 201–208

    PubMed  Google Scholar 

  34. Schoepf UJ, Holzknecht N, Helmberger TK et al. (2002) Subsegmental pulmonary emboli: improved detection with thin-collimation multi-detector row spiral CT. Radiology 222: 483–490

    PubMed  Google Scholar 

  35. Remy-Jardin M, Remy J, Artaud D et al. (1997) Peripheral pulmonary arteries: optimization of the spiral CT acquisition protocol. Radiology 204: 157–163

    PubMed  Google Scholar 

  36. Mollet NR, Cademartiri F, van Mieghem CA et al. (2005) High-resolution spiral computed tomography coronary angiography in patients referred for diagnostic conventional coronary angiography. Circulation 112: 2318–2323

    Article  PubMed  Google Scholar 

  37. Nikolaou K, Rist C, Wintersperger BJ et al. (2006) Clinical value of MDCT in the diagnosis of coronary artery disease in patients with a low pretest likelihood of significant disease. AJR Am J Roentgenol 186: 1659–1668

    Article  PubMed  Google Scholar 

  38. Giesler T, Baum U, Ropers D et al. (2002) Noninvasive visualization of coronary arteries using contrast-enhanced multidetector CT: influence of heart rate on image quality and stenosis detection. AJR Am J Roentgenol 179: 911–916

    PubMed  Google Scholar 

  39. Hong C, Becker CR, Huber A et al. (2001) ECG-gated reconstructed multi-detector row CT coronary angiography: effect of varying trigger delay on image quality. Radiology 220: 712–717

    PubMed  Google Scholar 

  40. Willmann JK, Weishaupt D, Lachat M et al. (2002) Electrocardiographically gated multi-detector row CT for assessment of valvular morphology and calcification in aortic stenosis. Radiology 225: 120–128

    PubMed  Google Scholar 

Download references

Interessenkonflikt

Es besteht kein Interessenskonflikt.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Thorsten R.C. Johnson.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Johnson, T., Nikolaou, K., Fink, C. et al. Dual-source-CT in der Diagnostik des Thoraxschmerzes. Radiologe 47, 301–309 (2007). https://doi.org/10.1007/s00117-007-1480-1

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00117-007-1480-1

Schlüsselwörter

Keywords

Navigation