Literatur
Benson AB 3rd, Venook AP, Bekaii-Saab T et al (2015) Rectal Cancer, Version 2.2015. J Natl Compr Canc Netw 13:719–728 (quiz 28)
Bundschuh RA, Dinges J, Neumann L et al (2014) Textural parameters of tumor heterogeneity in (1)(8)F-FDG PET/CT for therapy response assessment and prognosis in patients with locally advanced rectal cancer. J Nucl Med 55:891–897
Combs SE, Nusslin F, Wilkens JJ (2016) Individualized radiotherapy by combining high-end irradiation and magnetic resonance imaging. Strahlenther Onkol 192:209–215
Droge LH, Weber HE, Guhlich M et al (2015) Reduced toxicity in the treatment of locally advanced rectal cancer: a comparison of volumetric modulated arc therapy and 3D conformal radiotherapy. BMC Cancer 15:750
Eriksen MT, Wibe A, Haffner J et al (2007) Prognostic groups in 1,676 patients with T3 rectal cancer treated without preoperative radiotherapy. Dis Colon Rectum 50:156–167
Kulu Y, Hackert T, Debus J et al (2016) Role of neoadjuvant radiotherapy for rectal cancer : Is MRI-based selection a future model? Chirurg 87(7):573–578
Kulu Y, Tarantino I, Billeter AT et al (2016) Comparative outcomes of Neoadjuvant treatment prior to total mesorectal excision and total mesorectal excision alone in selected stage II/III low and mid rectal cancer. Ann Surg Oncol 23:106–113
Leccisotti L, Gambacorta MA, De Waure C et al (2015) The predictive value of 18 F-FDG PET/CT for assessing pathological response and survival in locally advanced rectal cancer after neoadjuvant radiochemotherapy. Eur J Nucl Med Mol Imaging 42:657–666
Ngan SY, Burmeister B, Fisher RJ et al (2012) Randomized trial of short-course radiotherapy versus long-course chemoradiation comparing rates of local recurrence in patients with T3 rectal cancer: Trans-Tasman Radiation Oncology Group trial 01.04. J Clin Oncol 30:3827–3833
Pox C, Aretz S, Bischoff SC et al (2013) S3-guideline colorectal cancer version 1.0. Z Gastroenterol 51:753–854
Rodel C, Graeven U, Fietkau R et al (2015) Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial. Lancet Oncol 16:979–989
Samuelian JM, Callister MD, Ashman JB et al (2012) Reduced acute bowel toxicity in patients treated with intensity-modulated radiotherapy for rectal cancer. Int J Radiat Oncol Biol Phys 82:1981–1987
Sauer R, Liersch T, Merkel S et al (2012) Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years. J Clin Oncol 30:1926–1933
Sautter-Bihl ML, Hohenberger W, Fietkau R et al (2014) MRI-based treatment of rectal cancer: is prognostication of the recurrence risk solid enough to render radiation redundant? Ann Surg Oncol 21:197–204
Sebag-Montefiore D, Stephens RJ, Steele R et al (2009) Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trial. Lancet 373:811–820
Taylor FG, Quirke P, Heald RJ et al (2014) Preoperative magnetic resonance imaging assessment of circumferential resection margin predicts disease-free survival and local recurrence: 5‑year follow-up results of the MERCURY study. J Clin Oncol 32:34–43
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Habermehl, D. Der selektive Verzicht auf die neoadjuvante Radio(chemo)therapie beim Rektumkarzinom entbehrt der Evidenz. Chirurg 87, 884–886 (2016). https://doi.org/10.1007/s00104-016-0279-x
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DOI: https://doi.org/10.1007/s00104-016-0279-x