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Molecular basis of strigolactone perception in root-parasitic plants: aiming to control its germination with strigolactone agonists/antagonists

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Abstract

The genus Striga, also called “witchweed”, is a member of the family Orobanchaceae, which is a major family of root-parasitic plants. Striga can lead to the formation of seed stocks in the soil and to explosive expansion with enormous seed production and stability once the crops they parasitize are cultivated. Understanding the molecular mechanism underlying the communication between Striga and their host plants through natural seed germination stimulants, “strigolactones (SLs)”, is required to develop the technology for Striga control. This review outlines recent findings on the SL perception mechanism, which have been accumulated in Striga hermonthica by the similarity of the protein components that regulate SL signaling in nonparasitic model plants, including Arabidopsis and rice. HTL/KAI2 homologs were identified as SL receptors in the process of Striga seed germination. Recently, this molecular basis has further promoted the development of various types of SL agonists/antagonists as seed germination stimulants or inhibitors. Such chemical compounds are also useful to elucidate the dynamic behavior of SL receptors and the regulation of SL signaling.

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Abbreviations

2-MN:

2-Methoxy-1-naphthaldehyde

5-DS:

5-Deoxystrigol

ASK1:

ARABIDOPSIS SKP-LIKE 1

ATPase:

Adenosine triphosphatase

CL:

Carlactone

CLA:

Carlactonoate

CLIM:

Covalently linked intermediate molecule

D14:

DWARF14

DSF:

Differential scanning fluorimetry

EAR:

Element binding factor-associated amphiphilic repression

GA:

Gibberellin

HTL:

HYPOSENSITIVE TO LIGHT

ITC:

Isothermal titration calorimetry

KAI2:

KARRIKIN INSENSITIVE2

KAR:

Karrikin

LGS1:

LOW GERMINATION STIMULANT 1

LRR:

Leucine-rich repeat

MAX2:

MORE AXILLARY GROWTH2

MP:

Methyl phenlactonoate

Nij-1:

Nijmegen-1

SCF:

SKP1-Cullin-F-box

SL:

Strigolactone

SLR1:

SLENDER RICE1

SMAX1:

SUPPRESSOR OF MAX2 1

SMXL:

SMAX1-Like

SOP:

Soporidine

SPL7:

Sphynolactone-7

TPR:

TOPLESS-related protein

YLG:

Yoshimulactone Green

YLGW:

YLG double

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Authors and Affiliations

  1. Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan

    Takuya Miyakawa, Yuqun Xu & Masaru Tanokura

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  1. Takuya Miyakawa
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  2. Yuqun Xu
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  3. Masaru Tanokura
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Correspondence to Masaru Tanokura.

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Miyakawa, T., Xu, Y. & Tanokura, M. Molecular basis of strigolactone perception in root-parasitic plants: aiming to control its germination with strigolactone agonists/antagonists. Cell. Mol. Life Sci. 77, 1103–1113 (2020). https://doi.org/10.1007/s00018-019-03318-8

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  • DOI: https://doi.org/10.1007/s00018-019-03318-8

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