Abstract
The authors describe a study of the pathogenicity of 95 strains ofCandida albicans, the typing of which was described in the previous paper. Mortality among mice after intravenous administration was not related to the sex of the mice or the age of the strain in the artificial culture, but to the number of yeast-like microorganism cells in the dose of inoculum. All the strains ofCandida albicans were to some extent pathogenic. The most pathogenic strains had tufts of small, spherical blastospores on the pseudomycelium, while the least pathogenic had large, elongated spores arranged on the pseudomycelium in whorls.
Abstract
Приводятся данные исследований патогенности 95 штаммов Candida albicans, типизация которых была дана в предшествовавшей работе. Исследования показали, что гибель мышей после внутривенного введения клеток С. albicans зависит не от пола мышей и не от возраста культуры штамма в искуственной почве, а от количества клеток дрожжей в прививочной дозе. Все штаммы Candida albicans оказались до известной степени патогенными. У наиболее патогенных штаммов бластоспоры мелкие и круглые, в виде хлопьев на псевдомицелии, у наименее патогеннын—бластоспоры крупные, продолговатые, в виде мутовок на псевдомицелии.
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Šandula, J., Kocková-Kratochvílová, A. & Zámečníková, M. GenusCandida berkhout. Folia Microbiol 8, 313–317 (1963). https://doi.org/10.1007/BF02868777
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DOI: https://doi.org/10.1007/BF02868777