Zusammenfassung
Periphere spindelzellige Karzinoide sind eine sehr seltene histologische Variante der pulmonalen Karzinoide, die wahrscheinlich eine unreifere und daher häufiger metastasierende Tumortype darstellen. Da es sich bei den Karzinoiden um «semimaligne» Tumore handelt, deren biologisches Verhalten mit der pathohistologischen Morphologie oft nicht übereinstimmt, ist die Resektion wie bei einem Karzinom zu fordern.
Bei unserer Patientin waren keine Metastasen und keine Anzeichen eines Karzinoidsyndroms festzustellen, der Tumor wurde durch Lobektomie entfernt.
Summary
Peripheral spindle cell carcinoid tumors of the lung are very rare, probably showing an increased tendency to metastasize. As the usual histologic criteria of malignancy cannot be applied to carcinoids, these tumors should be resected like carcinomas.
Our patient was asymptomatic, neither metastases nor a carcinoid syndrome could be found; the tumor was resected by lobectomy.
Literatur
Arrigoni, M. G., Woolner, L. B., Bernatz, P. E.: Atypical carcinoid tumors of the lung. J. Thorac. Cardiovasc. Surg. 64, 413 (1972).
Bensch, K. G., Corrin, B., Pariente, R., Spencer, H.: Oat-cell carcinoma of the lung. Its origin and relationship to bronchial carcinoid. Cancer 22, 1163 (1968).
Bensch, K. G., Gordon, G. B., Miller, L. R.: Electron microscopic and biochemical studies on the bronchial carcinoid tumor. Cancer 18, 592 (1965).
Bonikos, D. S., Bensch, K. G., Jamplis, R. W.: Peripheral pulmonary carcinoid tumors. Cancer 37, 1977 (1976).
Burcharth, F., Axelsson, C.: Lung carcinoids. Scand. J. Thorac. Cardiovasc. Surg. 7, 72 (1973).
Churg, A.: Large spindle cell variant of the peripheral carcinoid tumor. Arch. Pathol. Lab. Med. 101, 216 (1977).
Craig, I. D., Finley, R. J.: Spindle-cell carcinoid tumor of the lung; cytological, histopathologic and ultrastructural features. Acta Cyt. 495, (1981).
Dube, V. E.: Peripheral bronchial carcinoid with a spindle cell pattern. Arch. Pathol. 89, 374 (1970).
Fraser and Paré: Diagnosis of diseases of the chest, 2nd edition, vol. II, p. 982. Saunders, Philadelphia-London-Toronto 1978.
Gillespie, J. J., Luger, A. M., Callaway, L. A.: Peripheral spindle and carcinoid tumor: A review of its ultrastructure, differential diagnosis and biological behaviour. Hum. Pathol. 10, 601 (1979).
Godwin, J. D.: Carcinoid tumors: an analysis of 2837 cases. Cancer 36, 560 (1975).
Goodner, J. T., Berg, J. W., Watson, W. L.: The nonbenign nature of bronchial carcinoids and cylindromas Cancer 14, 539 (1961).
Gephardt, G. N., Belovich, D. M.: Catology of pulmonary carcinoid tumors. Acta cytol. 434, (1981).
Heilman, E., Feiner, H.: The role of electron microscopy in diagnosis of unusual peripheral lung tumors. Hum. Pathol. 5, 589 (1978).
Heimburger, I. L., Kilman, J. W., Battersby, J. S.: Peripheral bronchial adenomas. J. Thorac. Cardiovasc. Surg. 52, 542 (1966).
Jensik, R. L.: How extensive is the resection for bronchial adenoma?. Ann. Thorac. Surg. 19, 482 (1975).
Johnson, L. A. et al.: Carcinoids: The association of histological growth pattern and survival. Cancer 51, 882 (1983).
Kay, S.: Histologic and histogenetic observations of the peripheral adenoma of the lung. Arch. Pathol. 65, 395 (1958).
Kreyberg, L.: Histological typing of lung tumors. WHO, Genf 1967.
Kyriakos, M., Rochoff, S. D.: Brush biopsy of bronchial carcinoid; a source of cytological error. Acta cytol. 16, 261 (1972).
Okike, A., Bernatz, P. E., Woolner, L. B.: Carcinoid tumors of the lung. Ann. Thorac. Surg. 22, 270 (1976).
Okike, A., Bernatz, P. E., Payne, S., Woolner, L. B., Leonard, P. F.: Bronchoplastic procedures in the treatment of carcinoid tumors of the tracheobronchial tree. J. Thorac. Cardiovasc. Surg. 76, 281 (1978).
Salyer, D. C., Salyer, W. R., Eggleston, J. C.: Bronchial carcinoid tumors. Cancer 36, 1537 (1975).
Todd, T. R., Cooper, J. D., Weissberg, D., Delarve, N. C., Pearson, F. G.: Bronchial carcinoid tumors; twenty years experience. J. Thorac. Cardiovasc. Surg. 79, 532 (1980).
Turnbull, A. D., Huvos, A. G., Goodner, J. T., Beattie, E. J.: The malignant potential of bronchial adenoma. Ann. Thorac. Surg. 14, 453 (1972).
Wareing, T. H., Sawyers, J. L.: Carcinoids and the carcinoid syndrome. Am. J. Surg. 145, 769 (1983).
Williams, E. D., Sandler, M.: The classification of carcinoid tumors. Lancet I, 238 (1963).
Wilson, R. A.: An unusual second primary tumor: Report of a case of atypical carcinoid of the lung. Acta Cytol. 22, 362 (1978).
Wisniewsky, M., Fayemi, A. O.: Bronchial carcinoid: A malignant tumor. Chest 62, 760 (1972).
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Wandschneider, W., Pridun, N. Fallbericht eines peripheren spindelzelligen karzinoids der lunge. Acta Chir Austriaca 17, 71–74 (1985). https://doi.org/10.1007/BF02656414
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DOI: https://doi.org/10.1007/BF02656414