Abstract
A very rare case of multiple carcinoid tumors of the gallbladder and cystic duct is reported in a 77-year-old woman. Cholecystectomy and resection of the common bile duct, with regional lymph node dissection, were performed. The tumors consisted of a large mass (30×20×15mm) in the neck of the gallbladder and three small lesions in the cystic duct. Histologically, the tumor cells were arranged in solid nests, and showed many mitoses. Histochemical studies revealed argyrophilic and argentaffinic staining. Immunohistochemically, the tumor cells were positive for serotonin, chromogranin A, Leu 7, synaptophysin, and neuron-specific enolase. Thus, the present case was diagnosed as midguttype carcinoids.
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Ishibashi, T., Nagai, H., Yasuda, Y. et al. Multiple carcinoid tumors of the gallbladder and cystic duct. J Hep Bil Pancr Surg 2, 77–84 (1995). https://doi.org/10.1007/BF02348293
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DOI: https://doi.org/10.1007/BF02348293