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Evaluation of the mutagenic potential of bacterial polychlorinated biphenyl biodegradation products

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Abstract

Potential bacterial biodegradation products of polychlorobiphenyls (PCBs) were evaluated as environmental mutagens.p-Chlorophenylglyoxylic acid,p-chloromandelic acid and three monochlorinated benzoic acids were not mutagenic in either the sister chromatid exchange (SCE) orSalmonella typhimurium histidine reversion mutagenesis assays. Bacterial degradation may, therefore, tend to decrease the mutagenic potential of lesser chlorinated PCBs.

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Sayler, G.S., Reid, M.C., Perkins, B.K. et al. Evaluation of the mutagenic potential of bacterial polychlorinated biphenyl biodegradation products. Arch. Environ. Contam. Toxicol. 11, 577–581 (1982). https://doi.org/10.1007/BF01056365

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  • DOI: https://doi.org/10.1007/BF01056365

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