Summary
Human skin allografts cultured for approximately 6 weeks on a solid medium were transplanted to non-related human recipients with skin defects of various etiology. Although based on this study no answer could be given to the question whether these grafts survived or were replaced by cells of the recipient, it was observed that in most cases the grafts were not rejected and remained in situ several months up to over a year.
Zusammenfassung
Haut-Allograftkulturen (Vollhaut, subcutanes Gewebe entfernt oder dicke Dermatomschnitte) die 6 Wochen lang auf Festkulturen gezüchtet wurden, wurden auf Patienten mit Hautdefekten verschiedener Ursache transplantiert. Diese Transplantate wurden nicht abgestoßen und blieben für mehrere Monate bis 1 Jahr in situ lebensfähig. Die Frage, ob diese Transplantate überleben oder durch Empfängerzellen ersetzt wurden, wird diskutiert.
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Janssen de Limpens, A.M.P., Cormane, R.H. & Siddiqui, A.H. Allotransplantation of cultured human skin. Arch Dermatol Res 262, 323–328 (1978). https://doi.org/10.1007/BF00447368
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DOI: https://doi.org/10.1007/BF00447368