Summary
In 2 cases of AT, M-components are present in the serum, emphasizing the complexity of the immunological anomalies of this disease. These M-components allow comparisons between hereditary neurological diseases and viral diseases with slow evolution.
Zusammenfassung
In 2 Fällen von Ataxia telangiectasia finden sich im Serum M-Komponenten. Dies bezeugt die Komplexheit der immunologischen Anomalien dieser Erkrankung. Diese M-Komponenten legen einen Vergleich zwischen den erblichen neurologischen Erkrankungen und Virusinfektionen mit langsamem Verlauf nahe.
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Bibliography
Cawley, L. P., Schenken, J. R.: Monoclonal hypergammaglobulinemia of the γM type in a nine-year-old girl with ataxia-telangiectasia. Amer. J. clin. Path. 54, 790–801 (1970).
Lowenthal, A.: Agar gel electrophoresis in Neurology. Amsterdam-New York-London: Elsevier Publishing Company 1964.
Lowenthal, A., van Sande, M., Karcher, D.: Serum gamma globulins in 84 typical cases of subacute sclerosing panencephalitis. Neurology (Minneap.) 21, 277–280 (1971).
Pincus, J. H., Jaton, J. C., Bloch, K. J., Haber, E.: Properties of structurally restricted antibody to type VIII pneumococcal polysaccharide. J. Immunol. 104, 1149–1154 (1970).
Tabel, H., Ingram, D. G.: The immunoglobulins in Aleutian disease (viral plasmacytosis) of mink. Different types of hypergammaglobulinemias. Canad. J. comp. Med. 34, 329–332 (1970).
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Lowenthal, A., Adriaenssens, K., Colfs, B. et al. Oligoclonal gammopathy in ataxia-telangiectasia. Z. Neurol. 202, 58–63 (1972). https://doi.org/10.1007/BF00316426
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DOI: https://doi.org/10.1007/BF00316426