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Cell Analysis in Valved Microfluidic Devices

  • Conference paper
Micro Total Analysis Systems 2002

Abstract

A novel μTAS methodology for chemical cytometry is presented. Microfluidic chambers defined by microvalves are used to isolate and lyse cells, followed by fluorescent derivatization and separation of the cellular contents.

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References

  1. M. A. Unger, et al., Monolithic Microfabricated Valves and Pumps by Multilayer Soft Lithography, Science, pp. 113–116, (2000).

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  2. P. C. H. Li and D. J. Harrison, Transport, Manipulation, and Reaction of Biological Cells On-Chip Using Electrokinetic Effects, Analytical Chemistry, pp. 1564–1568, (1997).

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  3. C. T. Culbertson, et al., Rapid Cellular Assays on Microfluidic Devices, Proc. Micro Total Analysis Systems 2001, Kluwer Academic Publishers, Dordrecht, The Netherlands, pp. 285–286, (2001).

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  4. A. Wheeler, et al., CATH.A Neuron Cell Analysis on a Chip with Micellar Electrokinetic Chromatography, Proc. Micro Total Analysis Systems 2001, Dordrecht, The Netherlands, pp. 311–312, (2001).

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© 2002 Springer Science+Business Media Dordrecht

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Wheeler, A.R., Leach, A.M., Zare, R.N. (2002). Cell Analysis in Valved Microfluidic Devices. In: Baba, Y., Shoji, S., van den Berg, A. (eds) Micro Total Analysis Systems 2002. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-0504-3_67

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  • DOI: https://doi.org/10.1007/978-94-010-0504-3_67

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-3953-6

  • Online ISBN: 978-94-010-0504-3

  • eBook Packages: Springer Book Archive

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