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Part of the book series: Advances in Forensic Haemogenetics ((HAEMOGENETICS,volume 1))

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Abstract

Human blood coagulation factor 13, the fibrin stabilizing factor, is a zymogen which after activation by thrombin and calcium ions catalyses the formation of γ -glutamyl- ε -lysine cross links between fibrin molecules (Losowsky and Miloszewski, 1977). Factor 13 consists of two A subunits and two B subunits (A2B2) (Schwartz et al 1973). Both A and B subunits are found in plasma but only B subunits in serum. The B subunit has no enzymatic activity and may serve as a carrier molecule in plasma (Schwartz et al 1973).

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References

  • Board, P.G.: Genetic polymorphism of the A subunit of human coagulation factor XIII. Am. J. Hum. Genet. 31: 116–124 (1979)

    PubMed  CAS  Google Scholar 

  • Board, P.G.: Genetic polymorphism of the B subunit of human coagulation factor XIII. Am. J. Hum. Genet. 32: 348–353 (1980)

    PubMed  CAS  Google Scholar 

  • Kreckel, P., Kühnl, P.: Improved coagulation factor XIIIB (FXIIIB) phenotyping after neuraminidase treatment of plasma and first description of the FXIIIB2 phenotype. Blut 45: 337–345 (1982)

    Article  PubMed  CAS  Google Scholar 

  • Kreckel, P., Kühnl, P., Scharrer, I.: Formal genetics and population data of the A and B subunits of the fibrin stabilizing factor (factor XIII)-evidence for a rare FXIII*QL variant and a new allele, FXIIIB*4, pp. 81–89. In: R. Egbring and H.-G. Klingemann (eds.) Factor XIII and fibronectin. Die medizinische Verlagsgesellschaft, Marburg 1983 (1983)

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  • Losowsky, M.S., Miloszewski, K.J.A.: Factor XIII. Br. J. Haematol. 37: 1–5 (1977)

    PubMed  CAS  Google Scholar 

  • Mauff, G., Schilling, A., Pulverer, G.: Coagulation factor XIII: Deter-mination of the genetic polymorphism of subunit B (F13B) by immunoblotting in a West German population sample. 10th International Congress of the Society for Forensic Haemogenetics, Munchen, pp. 453–457 (1983)

    Google Scholar 

  • Olaisen, B., Siverts, A., Gedde-Dahl, T.Jr., Jonassen, R., Teisberg, P.: Coagulation factor 13A and -B Polymorphisms: 10th International Congress of the Society for Forensic Haemogenetics, Munchen, pp. 459–465 (1983)

    Google Scholar 

  • Schwartz, M.L., Pizzo, S.V., Hill, R.L., McKee, P.A.: Human factor XIII from plasma and platelets. J. Biol. Chem. 248: 1395–1407 (1973)

    PubMed  CAS  Google Scholar 

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© 1986 Springer-Verlag Berlin Heidelberg

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Hjalmarsson, K. (1986). Coagulation Factor 13B Polymorphism in Sweden. In: Brinkmann, B., Henningsen, K. (eds) 11th Congress of the Society for Forensic Haemogenetics (Gesellschaft für forensische Blutgruppenkunde e.V.). Advances in Forensic Haemogenetics, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71150-3_55

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  • DOI: https://doi.org/10.1007/978-3-642-71150-3_55

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-16500-2

  • Online ISBN: 978-3-642-71150-3

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