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Diastolic Pressure-Volume Relation and Left Ventricular Mass in Man After Autonomic Blockade and During Afterload Variation with Isosorbide Dinitrate and Methoxamine

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Nitrates III

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Abstract

Afterload variations alter the diastolic pressure-volume relation of the left ventricle. This effect could be due to extramyocardial factors, e.g., pericardium or right ventricular filling pressure. Changes in coronary perfusion pressure may, in addition, alter the diastolic pressure-volume relation by varying coronary vascular engorgement, which is accompanied by changes of the angiographically determined left ventricular muscle mass. The present study investigates the effect of acute afterload variations on left ventricular muscle mass and diastolic pressure-volume relations.

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References

  1. Brodie BR, McLaurin LP (1979) Effects of acute changes in systemic arterial pressure on left ventricular diastolic stiffness and mass. Br Heart J 42: 65

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Authors
  1. H. C. Mehmel
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  2. K. Ruffmann
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  3. K. v. Olshausen
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  4. G. Schuler
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  5. F. Schwarz
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  6. W. Kübler
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Editor information

Editors and Affiliations

  1. Abteilung für Kardiologie, Med. Hochschule Hannover, Karl-Wiechert-Allee 9, D-3000, Hannover 61, Germany

    P. R. Lichtlen

  2. Zentralkrankenhaus „Links der Weser“, Senator-Weßling-Straße, D-2800, Bremen 61, Germany

    H.-J. Engel

  3. Pharma-Schwarz GmbH, D-4019, Monheim, Germany

    A. Schrey

  4. Dept. of Cardiology, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, 90048, Los Angeles, Calif., USA

    H. J. C. Swan (Director) (Director)

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© 1981 Springer-Verlag Berlin Heidelberg

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Mehmel, H.C., Ruffmann, K., v. Olshausen, K., Schuler, G., Schwarz, F., Kübler, W. (1981). Diastolic Pressure-Volume Relation and Left Ventricular Mass in Man After Autonomic Blockade and During Afterload Variation with Isosorbide Dinitrate and Methoxamine. In: Lichtlen, P.R., Engel, HJ., Schrey, A., Swan, H.J.C. (eds) Nitrates III. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68085-4_22

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  • DOI: https://doi.org/10.1007/978-3-642-68085-4_22

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-68087-8

  • Online ISBN: 978-3-642-68085-4

  • eBook Packages: Springer Book Archive

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