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PET in Cardiovascular Diseases

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Positron Emission Tomography

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Abstract

Cardiovascular diseases are known to be the most frequent cause of disability and death in the employable population of the developed countries. In Russia, cardiovascular pathologies account for 55% of deaths. Most common (47%) among these diseases is coronary heart disease (CHD) (Vyalkov 2002; Oganov and Ya 2002). In Western Europe, the USA, Canada and Australia, mortality from ischemic heart disease has displayed a tendency to decrease over the last several decades. On the contrary, in Russia its growth is being observed. According to the expert committee of the Russian scientific society of cardiologists (2004), only 40–50% of the people who suffer from CHD are aware of their disease and receive adequate treatment, while in 50–60% of cases the disease remains undetected. In this light, it is obvious that improving early diagnosis of cardiovascular diseases with the aid of modern radiological methods can be of significant use in increasing the efficiency of secondary prevention of this pathology. Unfortunately, there still remains the idea in practical cardiology that selective coronography is the “gold standard” in diagnosing ischemic heart disease, since this method provides information on the anatomy of the coronary channel. Meanwhile this technique represents only the state of the intraluminal contour of coronary arteries and does not permit to thoroughly assess the functional significance of coronary stenoses. In addition, the procedure is invasive and may induce a number of complications, the most dangerous of them being hemorrhage from the area of puncture of femoral artery or damage of atherosclerotic plaques in the coronary artery orifices, which can entail embolism and provoke acute coronary syndrome with all consequences up to the lethal outcome.

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Authors and Affiliations

  1. Russian Research Center for Radiology and Surgery, St. Petersburg, Russia

    Anatoliy Granov

  2. Department of Radiology and Nuclear Medicine, Russian Research Center for Radiology, St. Petersburg, Russia

    Leonid Tiutin

  3. Department of Nuclear Medicine Division of Radiology, Medical University Graz, Graz, Austria

    Thomas Schwarz M.D.

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  1. Anatoliy Granov
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  2. Leonid Tiutin
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  3. Thomas Schwarz M.D.
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  1. Russian Research Center for Radiology an, Pesochny, ul. Leningradskaya 70, St. Petersburg, 197758, Russia

    Anatoliy Granov

  2. , Dept. of Radiology and Nuclear Medicine, Russian Research Center for Radiology, Pesochny, ul. Leningradskaya 70, St. Petersburg, 197758, Russia

    Leonid Tiutin

  3. , Klinische Abt. für Nuklearmedizin, Universitätsklinik für Radiologie, Auenbruggerplatz 9, Graz, Austria

    Thomas Schwarz

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Granov, A., Tiutin, L., Schwarz, T. (2013). PET in Cardiovascular Diseases. In: Granov, A., Tiutin, L., Schwarz, T. (eds) Positron Emission Tomography. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-21120-1_20

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