Zusammenfassung
Komplikationen in der Behandlung eines Typ-1-Diabetes entstehen entweder durch zu viel oder zu wenig Insulin im Blut. Wird relativ zu der körperlichen Bewegung und der Kohlenhydratzufuhr zu viel Insulin gespritzt, entstehen Unterzuckerungen (▸ Abschn. 11.1). Wurde abhängig vom Bedarf längerfristig zu wenig oder gar kein Insulin injiziert, dann droht eine ketoazidotische Entgleisung ▸ Kap. 12).
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Literatur
Cryer PE (1992) Iatrogenic hypoglycemia as a cause of hypoglycemiaassociated autonomic failure in IDDM: A vicious cycle. Diabetes 41: 255–260
DCCT (Diabetes Control and Complications Trial) Research Group (1996) Effects of intensive diabetes therapy on neuropsychological function in adults in the DCCT. Ann Intern Med 124: 379–388
DCCT (Diabetes Control and Complications Trial), Epidemiology of Diabetes Interventions and Complications Study Research Group, Jacobson AM et al. (2007) Long-term effect of diabetes and its treatment on cognitive function. N Engl J Med 356(18): 1842–1852
Ferguson SC, Blane A, Wardlaw J, Frier BM, Perros P, McCrimmon RJ, Deary IJ (2005) Influence of an early-onset age of type 1 diabetes on cerebral structure and cognitive function. Diabetes Care 28 (6): 1431–1437
Holterhus PM, Beyer P, Bürger-Büsing J et al. (2009) Diagnostik, Therapie und Verlaufskontrolle des Diabetes mellitus im Kindes-und Jugendalter. In: T Haak, M Kellerer (Hrsg) Leitlinie von diabtesDE und AGPD www.diabetesDE.org. Gesehen 29.6.2009
Jauch-Chara K, Hallschmid M, Gais S, Oltmanns KM, Peters A, Born J, Schultes B (2007) Awakening and counterregulatory response to hypoglycemia during early and late sleep. Diabetes 56 (7): 1938–1942
Mitrakou A, Ryan C, Veneman T et al. (1991) Hierarchy of glycemic thresholds for counterregulatory hormone secretion, symptoms, and cerebral dysfunction. Am J Physiol 260 (1 Pt 1): E67–74
Perantie DC, Lim A, Wu J et al. (2008) Effects of prior hypoglycemia and hyperglycemia on cognition in children with type 1 diabetes mellitus. Pediatr Diabetes 9 (2): 87–95
Peters A, Schweiger U, Pellerin L et al. (2004) The selfish brain: competition for energy resources. Neurosci Biobehav Rev 28 (2): 143–180
Rovet JF, Ehrlich RM (1999) The effect of hypoglycemic seizures on cognitive function in children with diabetes: a 7-year prospective study. J Pediatr 134 (4): 503–506
Schoenle EJ, Schoenle D, Molinari L, Largo RH (2002) Impaired intellectual development in children with type I diabetes: association with HbA(1c), age at diagnosis and sex. Diabetologia 45: 108–114
Schwab KO, Leichtenschlag EM, Martin C, Bartels H (1997) Symptoms of hypoglycaemia in children and adolescents with type 1 diabetes mellitus. Monatsschr Kinderheilkd 145: 120–127
Schwab KO, Menche U, Schmeisl G, Lohse MJ (2004) Hypoglycemiadependent beta2-adrenoceptor downregulation: a contributing factor to hypoglycemia unawareness in patients with type-1 diabetes? Horm Res 62 (3): 137–141 http://www.ncbi.nlm.nih.gov/ pubmed/15297801?ordinalpos=11&itool=EntrezSystem2.PEntrez. Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum. Gesehen am 29.6.2009
Schwartz NS, Clutter WE, Shah SD, Cryer PE (1987) Glycemic thresholds for activation of glucose counterregulatory systems are higher than the threshold for symptoms. J Clin Invest 79 (3): 777–781
Wagner VM, Rosenbauer J, Grabert M, Holl RW; German Initiative on Quality Control in Pediatric Diabetology (2008) Severe hypoglycemia, metabolic control, and diabetes management in young children with type 1 diabetes using insulin analogs — a follow-up report of a large multicenter database. Eur J Pediatr 167 (2): 241–242
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Schwab, K.O. (2010). Akute Komplikationen: Hypoglykämie. In: Pädiatrische Endokrinologie und Diabetologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-01912-8_11
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