Abstract
Supportive care is a key element in the management of transplant recipients and has probably contributed the most to their improved outcomes over the years. Important elements for the establishment of supportive care in a new transplant unit are discussed in other chapters, including the structure and isolation requirements for the in-patient unit and ambulatory care, the structure of the program and its healthcare teams supporting patient management, the required transfusional support, and laboratory requirements for patient management.
In this chapter, we aim to provide combined general guidance on the recommended practices for key aspects of supportive care and their implementation in a new transplant unit, including intravenous access, intensive care, antiemetic and pain relief, management of mucositis, nutritional support, drug toxicity, and anti-infective management.
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O’Grady NP, Alexander M, Burns LA, Dellinger EP, Garland J, Heard SO, et al. Guidelines for the prevention of intravascular catheter-related infections. Am J Infect Control. 2011;39(4 Suppl 1):S1–S34.
Parienti JJ, Mongardon N, Mégarbane B, Mira JP, Kalfon P, Gros A, et al. Intravascular complications of central venous catheterization by insertion site. N Engl J Med. 2015;373(13):1220–9.
Jenkins P, Johnston LJ, Pickham D, Chang B, Rizk N, Tierney DK. Intensive care utilization for hematopoietic cell transplant recipients. Biol Blood Marrow Transplant. 2015;21(11):2023–7.
Boyacı N, Aygencel G, Turkoglu M, Yegin ZA, Acar K, Sucak GT. The intensive care management process in patients with hematopoietic stem cell transplantation and factors affecting their prognosis. Hematology. 2014;19(6):338–45.
Orvain C, Beloncle F, Hamel JF, Thépot S, Mercier M, Kouatchet A, et al. Different impact of the number of organ failures and graft-versus-host disease on the outcome of allogeneic stem cell transplantation recipients requiring intensive care. Transplantation. 2016;101(2):437–44.
NCCN Guidelines. Antiemesis. Version 2. 2016. https://www.nccn.org.
MASCC/ESMO Antiemetic Guideline. 2016. http://www.mascc.org/antiemetic-guidelines.
Lalla RV, Bowen J, Barasch A, Elting L, Epstein J, Keefe DM, McGuire DB, et al. MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy. Cancer. 2014;120(10):1453–61.
Van der Meij BS, de Graaf P, Wierdsma NJ, Langius JA, Janssen JJ, van Leeuwen PA, et al. Nutritional support in patients with GVH-D of the digestive tract: state of the art. Bone Marrow Transplant. 2013;48(4):474–82.
Fuji S, Einsele H, Savani BN, Kapp M. Systematic nutritional support in allogeneic hematopoietic stem cell transplant recipients. Biol Blood Marrow Transplant. 2015;21(10):1707–13.
Bozzetti F, Arends J, Lundholm K, Micklewright A, Zurcher G, Muscaritoli M, ESPEN. ESPEN guidelines on parenteral nutrition: non-surgical oncology. Clin Nutr. 2009;28(4):445–54.
Imataki O, Nakatani S, Hasegawa T, Kondo M, Ichihashi K, Araki M, et al. Nutritional support for patients suffering from intestinal graft-versus-host disease after allogeneic hematopoietic stem cell transplantation. Am J Hematol. 2006;81(10):747–52.
NCCN Guidelines. Adult Cancer Pain. Version 2. 2016. https://www.nccn.org.
Niscola P, Cupelli L, Romani C, Scaramucci L, Dentamaro T, Tendas A, et al. Mucositis in patients with hematological malignancies: an overview. Haematologica. 2007;92(2):222–31.
Ripamonti CI, Santini D, Maranzano E, Berti M, Roila F, ESMO Guidelines Working Group. Management of cancer pain: ESMO Clinical Practice Guidelines. Ann Oncol. 2012;23(Suppl 7):vii139–54.
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Duarte, R.F., Sánchez-Ortega, I. (2018). Supportive Care. In: Gluckman, É., Niederwieser, D., Aljurf, M. (eds) Establishing a Hematopoietic Stem Cell Transplantation Unit . Springer, Cham. https://doi.org/10.1007/978-3-319-59358-6_12
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DOI: https://doi.org/10.1007/978-3-319-59358-6_12
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