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Anticoagulation in Cardiac Patients

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Precision Anticoagulation Medicine

Abstract

Anticoagulation in cardiac patients is somewhat complex and may increase the risk of bleeding as most of these patients are on antiplatelets or antithrombotic agents. Based on the current guidelines, it is therefore important to tailor the use of such agents. This chapter describes the use of anticoagulants and antiplatelet agents in the context of atrial fibrillation in heart failure and in patients with valvular heart disease as well as for those undergoing percutaneous coronary interventions.

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Abbreviations

ACC:

American College of Cardiologists

ACCP:

American College of Chest Physicians

AHA:

American Heart Association

AF:

Atrial fibrillation

ASA:

Acetylsalicylic acid

AVR:

Aortic valve replacement

BHV:

Bioprosthetic heart valve

BMS:

Bare metal stent

CAD:

Coronary artery disease

CCS:

Canadian Cardiovascular Society

CHADS:

Scoring system for atrial fibrillation

CHF:

Congestive heart failure

DES:

Drug-eluting stent

EF:

Ejection fraction

ESC:

European Society of Cardiology

HFpEF:

Heart failure with preserved ejection fraction

HFrEF:

Heart failure with reduced ejection fraction

LVEF:

Left ventricular ejection fraction

MHVs:

Mechanical heart valves

MVR:

Mitral valve replacement

MVRep:

Mitral valve repair

NOACs:

Non-vitamin K antagonist (VKA) oral anticoagulants

NVAF:

Nonvalvular atrial fibrillation

OACs:

Oral anticoagulants

PCI:

Percutaneous coronary intervention

ST:

Stent thrombosis

STEMI:

ST-segment elevation myocardial infarction

STS:

Society of Thoracic Surgeons

TAVR :

Transcatheter aortic valve replacement

TE:

Thromboembolism

TIA:

Transient ischemic attack

VAF:

Valvular atrial fibrillation

VHD:

Valvular heart disease

VKA:

Vitamin K antagonist

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Haddad, H., Okpalauwaekwe, U., Sharma, N., Shavadia, J.S., Zhai, A., Haddad, T. (2020). Anticoagulation in Cardiac Patients. In: Goubran, H., Ragab, G., Hassouna, S. (eds) Precision Anticoagulation Medicine. Springer, Cham. https://doi.org/10.1007/978-3-030-25782-8_3

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