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Analysis of Physiological Responses to Thyroid Hormones and Their Receptors in Bone

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Thyroid Hormone Nuclear Receptor

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1801))

Abstract

Thyroid hormone has profound effects on skeletal development and adult bone maintenance. Here, we review the current literature concerning thyroid hormone action in bone and cartilage in relation to human disease and animal models. We describe state-of-the-art imaging and biomechanical methods used to determine structural and functional parameters in the skeletal phenotyping of mouse models.

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Authors and Affiliations

  1. Department of Medicine, Molecular Endocrinology Laboratory, Imperial College London, London, UK

    J. H. Duncan Bassett & Graham R. Williams

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  1. J. H. Duncan Bassett
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  2. Graham R. Williams
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Correspondence to J. H. Duncan Bassett or Graham R. Williams .

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  1. Centre Léon Bérard, Cancer Research Center of Lyon, Lyon, France

    Michelina Plateroti

  2. École normale supérieure de Lyon, Lyon, France

    Jacques Samarut

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Duncan Bassett, J.H., Williams, G.R. (2018). Analysis of Physiological Responses to Thyroid Hormones and Their Receptors in Bone. In: Plateroti, M., Samarut, J. (eds) Thyroid Hormone Nuclear Receptor. Methods in Molecular Biology, vol 1801. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7902-8_12

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  • DOI: https://doi.org/10.1007/978-1-4939-7902-8_12

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