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Psychopharmacologic Agents and Psychiatric Drug Considerations

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Essentials of Pharmacology for Anesthesia, Pain Medicine, and Critical Care

Abstract

The clinical anesthesiologist should appreciate that mental illnesses, cognitive disorders, and mental health problems affect all walks of life. It is a fact that few families in America are untouched by mental illness. An estimated 26.2 % of Americans aged 18 and older suffer from a diagnosable mental disorder in a given year. Mental disease interferes with life activity and ability to function and constitutes a pervasive and prevalent health problem among varied American population subsets, including the young and the elderly. The presence of mental disorders, associated symptoms, possible concomitant pathology, and prescribed medications is of significance to all health-care providers and not simply those in the field of mental health.

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References

  1. SG-Report: http://www.surgeongeneral.gov/library/mentalhealth/chapter2/sec2_1.html#epidemiology.

  2. Kessler RC, Chiu WT, Demler O, Walters EE. Prevalence, severity, and comorbidity of twelve-month DSM-IV disorders in the National Comorbidity Survey Replication (NCS-R). Arch Gen Psychiatry. 2005;62(6):617–27.

    Article  PubMed Central  PubMed  Google Scholar 

  3. Derrer SA, Helfaer MA. Evaluation of the psychiatric patient. In: Rogers MC, Tinker JH, Covino BG, Longnecker DE, editors. Principles and practice of anesthesiology. St. Louis: Mosby-Year Book; 1993. p. 567–74.

    Google Scholar 

  4. Barkin RL, Schwer WA, Barkin SJ. Recognition and management of depression in primary care: a focus on the elderly: a pharmacotherapeutic overview of the selection process among the traditional and new antidepressants. Am J Ther. 1999;7:205–26.

    Article  Google Scholar 

  5. Zito JM, Safer DJ, dosReis S, et al. Rising prevalence of antidepressants among US youth. Pediatrics. 2002;109:721–7.

    Article  PubMed  Google Scholar 

  6. Haddox JD, Chapkowski SL. Neuropsychiatric drug use in pain management. In: Raj PP, Abrams BM, Benzon HT, et al., editors. Practical management of pain. 3rd ed. St. Louis: Mosby; 2000. p. 489–512.

    Google Scholar 

  7. Stevens JC, Wrighton SA. Interaction of the enantiomers of fluoxetine and norfluoxetine with human liver cytochrome P450. J Pharmacol Exp Ther. 1993;266:964–71.

    CAS  PubMed  Google Scholar 

  8. Kaizar EE, Greenhouse JB, Seltman H, Kelleher K. Do antidepressants cause suicidality in children? A Bayesian meta-analysis. Clin Trials. 2006;3(2):73–90; discussion 91–8.

    Article  PubMed  Google Scholar 

  9. Gibbons RD, Brown CH, Hur K, Marcus SM, Bhaumik DK, Mann JJ. Relationship between antidepressants and suicide attempts: an analysis of the Veterans Health Administration data sets. Am J Psychiatry. 2007;164(7):1044–9.

    Article  PubMed  Google Scholar 

  10. Veith RC, Raskind MA, Caldwell JH, et al. Cardiovascular effects of tricyclic antidepressants in depressed patients with chronic heart disease. N Engl J Med. 1982;306:954–9.

    Article  CAS  PubMed  Google Scholar 

  11. El-Ganzouri AR, Ivankovich AD, Braverman B, et al. Monoamine oxidase inhibitors: should they be discontinued preoperatively? Anesth Analg. 1985;64:592–6.

    Article  CAS  PubMed  Google Scholar 

  12. Wong KC. Preoperative discontinuation of monoamine oxidase inhibitor therapy: an old wives’ tale. Semin Anesthesiol. 1986;5:145–8.

    Google Scholar 

  13. Browne B, Linter S. Monoamine oxidase inhibitors and narcotic analgesics: a critical review of the implications for treatment. Br J Psychiatry. 1987;151:210–2.

    Article  CAS  PubMed  Google Scholar 

  14. Hill GE, Wong KC, Hodges MR. Lithium carbonate and neuromuscular blocking agents. Anesthesiology. 1977;46:122–6.

    Article  CAS  PubMed  Google Scholar 

  15. Lichtor JL. Anesthesia for ambulatory surgery. In: Barash PG, Cullen BF, Stoelting RK, editors. Clinical anesthesia. 4th ed. Philadelphia: Lippincott Williams & Wilkins; 2001. p. 1217–38.

    Google Scholar 

  16. Geiduschek J, Cohen SA, Khan A, Cullen BF. Repeated anesthesia for a patient with neuroleptic malignant syndrome. Anesthesiology. 1988;68:134–7.

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Charles Fox MD .

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Chemical Structures

Chemical Structures

Chemical Structure 36.1
figure 1

Citalopram

Chemical Structure 36.2
figure 2

Escitalopram

Chemical Structure 36.3
figure 3

Glycopyrrolate

Chemical Structure 36.4
figure 4

Haloperidol

Chemical Structure 36.5
figure 5

Ziprasidone

Chemical Structure 36.6
figure 6

Chlorpromazine

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Fox, C., Kaye, A.D., Liu, H. (2015). Psychopharmacologic Agents and Psychiatric Drug Considerations. In: Kaye, A., Kaye, A., Urman, R. (eds) Essentials of Pharmacology for Anesthesia, Pain Medicine, and Critical Care. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-8948-1_36

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  • DOI: https://doi.org/10.1007/978-1-4614-8948-1_36

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  • Publisher Name: Springer, New York, NY

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  • Online ISBN: 978-1-4614-8948-1

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