Skip to main content

Prostate Tissue Banking

  • Chapter
  • First Online:
Prostate Cancer: A Comprehensive Perspective

Abstract

As the most common non-dermatologic malignancy affecting males in the Western world, and the second leading cause of male cancer-related deaths, the importance of prostate cancer research needs little justification [1]. Epidemiologic reports have described the significant heritability of such malignancies, with one twin-study attributing 42 % (CI 29–50 %) of prostate cancer cases to heritable factors [2]. Genome-wide linkage analyses of germline single nucleotide polymorphisms (SNPs) continue to uncover many low-risk genetic associations with prostate cancer [3]. These findings are being supplemented with expression arrays in an effort to identify individual somatic mutations such as TMPRSS2-ERG gene fusions [4] as well as more global gene expression profiles.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 229.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Jemal A, Siegel R, Xu J, et al. Cancer statistics, 2010. CA Cancer J Clin. 2010;60:277.

    Article  PubMed  Google Scholar 

  2. Lichtenstein P, Holm NV, Verkasalo PK, Iliadou A, Kaprio J, Koskenvuo M, Pukkala E, Skytthe A, Hemminki K. Environmental and heritable factors in the causation of cancer–analyses of cohorts of twins from Sweden, Denmark, and Finland. N Engl J Med. 2000;343(2):78–85.

    Article  PubMed  CAS  Google Scholar 

  3. Witte J. Prostate cancer genomics: toward a new understanding. Nat Rev Genet. 2009;10(2):77–82.

    Article  PubMed  CAS  Google Scholar 

  4. Setlur SR, et al. Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer. J Natl Cancer Inst. 2008;100:815–25.

    Article  PubMed  CAS  Google Scholar 

  5. Zheng SL, et al. Cumulative association of five genetic variants with prostate cancer. N Engl J Med. 2008;358:910–9.

    Article  PubMed  CAS  Google Scholar 

  6. Kumar-Sinha C, Tomlins SA, Chinnaiyan AM. Recurrent gene fusions in prostate cancer. Nat Rev Cancer. 2008;8:497–511.

    Article  PubMed  CAS  Google Scholar 

  7. Tewari AK, Rao S, Martinez-Salamanca JI, Leung R, Ramanathan R, Mandhani A, Vaughan ED, Menon M, Horninger W, Tu J, Bartsch G. Cancer control and the preservation of neurovascular tissue: how to meet competing goals during robotic radical prostatectomy. BJU Int. 2008;101(8):1013–8.

    Article  PubMed  Google Scholar 

  8. Hollenbeck BK, Bassily N, Wei JT, Montie JE, Hayasaka S, Taylor JM, Rubin MA. Whole mounted radical prostatectomy specimens do not increase detection of adverse pathological features. J Urol. 2000;164(5):1583–6.

    Article  PubMed  CAS  Google Scholar 

  9. Dev H, Rickman D, Sooriakumaran P, Srivastava A, Grover S, Leung R, Kim R, Kitabayashi N, Esqueva R, Park K, Padilla J, Rubin M, Tewari A. Biobanking after robotic-assisted radical prostatectomy: a quality assessment of providing prostate tissue for RNA studies. Prostate Cancer Prostatic Dis. J Transl Med. 2011 Jul 26;9:121.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ashutosh K. Tewari M.D., MCh .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2013 Springer-Verlag London

About this chapter

Cite this chapter

Dev, H., Sooriakumaran, P., Tewari, A.K. (2013). Prostate Tissue Banking. In: Tewari, A. (eds) Prostate Cancer: A Comprehensive Perspective. Springer, London. https://doi.org/10.1007/978-1-4471-2864-9_16

Download citation

  • DOI: https://doi.org/10.1007/978-1-4471-2864-9_16

  • Published:

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-2863-2

  • Online ISBN: 978-1-4471-2864-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics