Abstract
The 1,3-dipolar cycloaddition of unstabilized azomethine ylide, which is generated in situ from isatin and thiaproline, to arylidene derivatives of rhodanine affords bis-spirofused thiapyrrolizidinooxindoles. The 1,3-dipolar addition reactions under consideration are fully regio- and diastereoselective.
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Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 8, pp. 1642–1645, August, 2012.
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Shvets, A.A., Nelyubina, Y.V., Lyssenko, K.A. et al. Synthesis of bis-spirofused thiapyrrolizidinooxindoles by 1,3-dipolar cycloaddition. Russ Chem Bull 61, 1659–1662 (2012). https://doi.org/10.1007/s11172-012-0227-y
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DOI: https://doi.org/10.1007/s11172-012-0227-y