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Preparation of [66Ga]bleomycin complex as a possible PET radiopharmaceutical

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Summary

Gallium-66 (T1/2 = 9.49 h) is an interesting radionuclide that has potential use for positron emission tomography (PET) imaging of biological processes in intermediate to slow target tissue uptake. 66Ga was produced in the NRCAM cyclotron as a result of 15 MeV proton bombardment of 66Zn with current intensity of 180 μA (yield 11.2 mCi/μAh). Bleomycin (BLM) was labeled with [66Ga]GaCl3

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Authors and Affiliations

  1. Cyclotron/Nuclear Medicine Department, Nuclear Research Center for Agriculture and Medicine, P.O. Box 31585-4395, Karaj, Iran

    A. R. Jalilian

  2. Cyclotron/Nuclear Medicine Department, Nuclear Research Center for Agriculture and Medicine, P.O. Box 31585-4395, Karaj, Iran

    P. Rowshanfarzad

  3. SSDL/Health Physics Department, Nuclear Research Center for Agriculture and Medicine, P.O. Box 31585-4395, Karaj, Iran

    M. Sabet

  4. Ion Beam Application Department, Nuclear Research Center for Agriculture and Medicine, P.O. Box 31585-4395, Karaj, Iran

    A. Novinrooz

  5. Cyclotron/Nuclear Medicine Department, Nuclear Research Center for Agriculture and Medicine, P.O. Box 31585-4395, Karaj, Iran

    G. Raisali

Authors
  1. A. R. Jalilian
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  2. P. Rowshanfarzad
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  3. M. Sabet
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  4. A. Novinrooz
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  5. G. Raisali
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Jalilian, A., Rowshanfarzad, P., Sabet, M. et al. Preparation of [66Ga]bleomycin complex as a possible PET radiopharmaceutical. J Radioanal Nucl Chem 264, 617–621 (2005). https://doi.org/10.1007/s10967-005-0761-2

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  • DOI: https://doi.org/10.1007/s10967-005-0761-2

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