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Accurate estimation of global and regional cardiac function by retrospectively gated multidetector row computed tomography

Comparison with cine magnetic resonance imaging

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Abstract

Retrospective reconstruction of ECG-gated images at different parts of the cardiac cycle allows the assessment of cardiac function by multi-detector row CT (MDCT) at the time of non-invasive coronary imaging. We compared the accuracy of such measurements by MDCT to cine magnetic resonance (MR). Forty patients underwent the assessment of global and regional cardiac function by 16-slice MDCT and cine MR. Left ventricular (LV) end-diastolic and end-systolic volumes estimated by MDCT (134±51 and 67±56 ml) were similar to those by MR (137±57 and 70±60 ml, respectively; both P=NS) and strongly correlated (r=0.92 and r=0.95, respectively; both P<0.001). Consequently, LV ejection fractions by MDCT and MR were also similar (55±21 vs. 56±21%; P=NS) and highly correlated (r=0.95; P<0.001). Regional end-diastolic and end-systolic wall thicknesses by MDCT were highly correlated (r=0.84 and r=0.92, respectively; both P<0.001), but significantly lower than by MR (8.3±1.8 vs. 8.8±1.9 mm and 12.7±3.4 vs. 13.3±3.5 mm, respectively; both P<0.001). Values of regional wall thickening by MDCT and MR were similar (54±30 vs. 51±31%; P=NS) and also correlated well (r=0.91; P<0.001). Retrospectively gated MDCT can accurately estimate LV volumes, EF and regional LV wall thickening compared to cine MR.

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Acknowledgements

We would like to thank Alain Vlassenbroeck and Mani Vembar from Philips Medical Systems for technical assistance.

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Authors and Affiliations

  1. Division of Cardiology, Université Catholique de Louvain, Brussels, Belgium

    Bénédicte Belge, Agnès Pasquet, Jean-Louis J. Vanoverschelde & Bernhard L. Gerber

  2. Division of Radiology, Université Catholique de Louvain, Brussels, Belgium

    Emmanuel Coche

  3. Department of Cardiology, Cliniques Universitaires St. Luc UCL, Av Hippocrate 10/2806, B-1200, Woluwe St. Lambert, Belgium

    Bernhard L. Gerber

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  1. Bénédicte Belge
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  2. Emmanuel Coche
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  3. Agnès Pasquet
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  5. Bernhard L. Gerber
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Correspondence to Bernhard L. Gerber.

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Grant funding: Dr. Belge was supported by a fellowship of the Fondation Nationale de la Recherche Scientifique of the Belgian government. Dr. Gerber was supported by a grant from the Fondation Nationale de la Recherche Scientifique of the Belgian government (FRSM 3.4557.02).

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Belge, B., Coche, E., Pasquet, A. et al. Accurate estimation of global and regional cardiac function by retrospectively gated multidetector row computed tomography. Eur Radiol 16, 1424–1433 (2006). https://doi.org/10.1007/s00330-006-0169-6

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  • DOI: https://doi.org/10.1007/s00330-006-0169-6

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