Abstract
An 83-year-old man with testicular lymphoma demonstrated progressive scrotal enlargement with non-homogeneity sonographically and abnormally increased uptake in the scrotum of Tc-99m HMDP and Tc-99m MIBI scintigraphically. Extensive bone/bone marrow metastases were exhibited by Tc-99m MIBI and Tc-99m HMDP scintigraphies and MRI of the spine. In addition, focal/tubular activity of the femoral bone marrow on Tc-99m MIBI imaging was consistent with skeletal scintigraphic findings. It is emphasized that Tc-99m MIBI total body imaging enabled the demonstration of testicular lymphoma as increased uptake and the illustration of skeletal/bone marrow metastases as diffuse and/or focal increased uptake, especially focal/tubular MIBI activity of the femoral marrow.
Similar content being viewed by others
References
Lu G, Shih W-J, Huang H-Y, et al. Tc-99m MIBI mammoscintigraphy of breast masses: early and delayed imaging.Nucl Med Commun 16: 150–156, 1995.
Khalkhali I, Mena I, Jouanne E, et al. Prone scintimammography in patients with suspicion of carcinoma of the breast.J Am Coll Surg 178: 491–497, 1994.
Burak Z, Argon M, Memis A, et al. Evaluation of palpable breast masses with Tc-99m MIBI: A comparative study with mammography and ultrasonography.Nucl Med Commun 15: 604–612, 1994.
O’Doherty MJ, Kettle AG, Wells P, et al. Parathyroid imaging with technetium-99m sestamibi: preoperative localization and tissue uptake studies.J Nucl Med 33: 313–318, 1992.
Lu G, Shih W-J, Xiu J-Y. Tc-99m MIBI uptake in recurrent parathyroid carcinoma and brown tumors.J Nucl Med 36: 811–813, 1995.
O’Driscoll CM, Baker F, Casey MJ, et al. Localization of recurrent medullary thyroid carcinoma with technetium-99m-methoxybutylisonitrile scintigraphy: a case report.J Nucl Med 32: 2281–2283, 1991.
Hassan IM, Sahweil A, Constantinides C, et al. Uptake and kinetics of Tc-99m hexakis 2-methoxyisobutyl isonitrile in benign and malignant lesions in the lungs.Clin Nucl Med 14: 333–340, 1989.
Aktolun C, Bayhan H, Kir M. Clinical experience with Tc-99m MIBI imaging in patients with malignant tumors: Preliminary results and comparison with Tl-201.Clin Nucl Med 17: 171–176, 1992.
O’Tuama LA, Packard AB, Treves ST. SPECT imaging of pediatric brain tumor with hexakis (methoxyisobutyl-isonitrile) technetium (I).J Nucl Med 31: 2040–2041, 1990.
Shih WJ, Kadzielawak K, Lee C, Moody EB, Ryo UK. Tc-99m sestamibi uptake by cerebellar metastasis from bronchogenic carcinoma.Clin Nucl Med 18: 887–890, 1993.
Medolago G, Virotta G, Piti A, et al. Abnormal uptake of technetium-99m hexakis-2-methoxyisobutyl isonitrile in a primary cardiac lymphoma.Eur J Nucl Med 199: 222–225, 1992.
Wakasugi S, Teshima H, Nakamura H, Hashizume T, Maeda T, Hiraoka A, et al. Tc-99m MIBI localization in bone marrow: A marker of bone marrow malignancy.Clin Nucl Med 23: 664–671, 1998.
Kricum ME. Red-yellow marrow conversion: Its effect on the location of some solitary bone lesions.Skeletal Radioln 14: 10, 1985.
Caner B, Kitapci M, Aras T, Erbengi G, Ugur O, Bekdik C. Increased accumulation of hexakis (2-methoxyisobutyl-isonitrile) technetium (I) in osteosarcoma in its metastatic lymph nodes.J Nucl Med 32: 1977–1978, 1991.
Reiman RE, Fetters JK. Localization of Tc-99m MIBI in diffuse myelodysplastic processes.J Nucl Med 37: 471–473, 1996.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Shih, WJ., Kwolek, D.S. & Lahr, B. Testicular lymphoma with bone/bone marrow metastases illustrated by scrotal sonography, spinal MRI, and total body Tc-99m HMDP and Tc-99m MIBI imagines. Ann Nucl Med 13, 293–297 (1999). https://doi.org/10.1007/BF03164866
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF03164866