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Specific binding of triiodothyronine to the nucleoplasm

  • Experimental Biology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The study of the binding of thyroid hormones to the nucleoplasm demonstrates the presence of triiodothyronine-binding molecules characterized by high affinity and limited binding capacity. The binding of thyroid analogs correlates with their thyromimetic activity. Sucrose gradient ultracentrifugation of triiodothyronine-labeled nuclear extract reveals the presence of triiodothyronine receptors, ribonucleoprotein particles with a sedimentation coefficient about 30S.

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Authors and Affiliations

  1. Laboratory of Regulation of Gene Expression, Institute of Genetics, Academy of Sciences of the Uzbekistan Republic, Tashkent

    A. T. Adylova & Ya. Kh. Turakulov

Authors
  1. A. T. Adylova
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  2. Ya. Kh. Turakulov
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Translated fromByulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 123, No. 2, pp. 219–221, February, 1997

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Adylova, A.T., Turakulov, Y.K. Specific binding of triiodothyronine to the nucleoplasm. Bull Exp Biol Med 123, 190–192 (1997). https://doi.org/10.1007/BF02766449

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  • DOI: https://doi.org/10.1007/BF02766449

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