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Bioefficacy Evaluation of Indigenously Developed Long-Lasting Insecticidal Net (LLIN) ‘Defender Net™’ for Control of Mosquitoes and Their Diseases in India

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Genetically Modified and other Innovative Vector Control Technologies

Abstract

Indigenous technology for long-lasting insecticidal mosquito net (LLIN) of monofilament of polyethylene was developed by Defence Research and Development Organisation (DRDO), named as Defender Net™, which is effective against mosquitoes in their varied Indian geoclimatic conditions. Defender Net™ contains a synthetic pyrethroid insecticide, deltamethrin at 0.15% ww or 55 a.i./sq.m. and a synergist piperonyl butoxide (PBO) at 0.55% ww and licensed under 9 (3B) of the Insecticides Act in India. Defender Net™ was found effective against disease vectors like Anopheles stephensi, Aedes aegypti and Culex quinquefasciatus in laboratory bioassay (phase I) even after 20 washings. Cx. quinquefasciatus is a sturdy mosquito among tested three species and very common in India. Defender Net™ was found effective against malaria vectors and safe to the users in the malaria-endemic Assam state and various culicines and mansonoides in the lymphatic filariasis (LF) as well as Japanese encephalitis (JE)-endemic Tamil Nadu state in a 3-year long investigation (phase II). Defender Net™ can be effectively incorporated within the Integrated Vector Management (IVM) strategy for any mosquito-borne disease management especially in the difficult frontier areas in the country.

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Acknowledgements

We are thankful to the villagers who volunteered for participation in the present study both in Assam and Tamil Nadu. Village headmen and selected village health workers are sincerely thanked for their keen interest and assistance in the study. Help of health staff of Missamari sub-centre and Gorubandha sub-centre as well as that of Centre for Research in Medical Entomology, Madurai, is hereby deeply thanked. Logistic support provided by the 71 infantry division and other army units is gratefully acknowledged.

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Veer, V. et al. (2021). Bioefficacy Evaluation of Indigenously Developed Long-Lasting Insecticidal Net (LLIN) ‘Defender Net™’ for Control of Mosquitoes and Their Diseases in India. In: Tyagi, B.K. (eds) Genetically Modified and other Innovative Vector Control Technologies. Springer, Singapore. https://doi.org/10.1007/978-981-16-2964-8_16

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