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Trypanosoma sp. infection in Boa constrictor snakes: morphological, hematological, clinical biochemistry, molecular, and phylogenetic characteristics
There are few reports of Trypanosoma in snakes, as well as little information about its pathogenicity in these animals. Thus, the present study aimed...
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Comparative pathogenicity of drug-resistant and drug-sensitive Trypanosoma brucei and Trypanosoma congolense infections in Nigerian local dogs
Animal trypanosomosis is an important endemic and wasting disease in sub-Saharan Africa. Its control relies on chemotherapy, and resistance to...
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Histological, haematological, and thyroid hormones toxicity of female rats orally exposed to CuO/ZnO core/shell nanoparticles synthesized by Ar plasma jets
Advancements in nanomedicine helped scientists design a new class of nanoparticles known as hybrid nanoparticles (core/shell) for diagnostic and...
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Observational longitudinal study on Toxoplasma gondii infection in fattening beef cattle: serology and associated haematological findings
Toxoplasmosis, caused by the protozoan parasite Toxoplasma gondii , is a globally distributed zoonotic infection with significant implications for...
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Studies on the effect of curcumin and quercetin in the liver of male albino rats exposed to gamma irradiation
Ionizing radiation produces deleterious effects on living organisms. The present investigation has been carried out to study the prophylactic as well...
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Effects of recreational scuba diving on erythropoiesis–“normobaric oxygen paradox” or “plasma volume regulation” as a trigger for erythropoietin?
PurposePrevious studies have shown an increase in erythrocyte lipid peroxidation and a decrease in red blood cell (RBC) count, hemoglobin, and...
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Racial differences in serological markers across the first year of injury in spinal cord injury: a retrospective analysis of a multi-center interventional study
Study designSecondary analysis of a randomized, multi-center, placebo-controlled study(Sygen®).
ObjectivesTo evaluate racial differences in...
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Sublethal pulmonary toxicity screening of silica nanoparticles in rats after direct intratracheal instillation
The present aimed to characterize the toxicity of silica nanoparticles in Sprague Dawley rats and determine the dose levels for a repeated-dose...
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Biomarkers of gastrointestinal nematodes in beef cattle raised in a tropical area
Biomarkers are specific molecular, histological, or physiological characteristics of normal or pathogenic biological processes and are promising in...
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Detection of Transversions and Transitions in HBG2 Cis-Elements Associated with Sickle Cell Allele in Ghanaians
Short tandem repeats located 5ʹ prime to the β-globin gene, have been observed to be in linkage disequilibrium with the HbS allele, and thought to...
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Saline extract of Portulaca elatior leaves with photoprotective and antioxidant activities does not show acute oral and dermal toxicity in mice
The present study aimed to evaluate saline extracts from the leaves (LE) and stem (SE) of Portulaca elatior in relation to their phytochemical...
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Machine learning-based improvement of MDS-CBC score brings platelets into the limelight to optimize smear review in the hematology laboratory
BackgroundMyelodysplastic syndromes (MDS) are clonal hematopoietic diseases of the elderly characterized by chronic cytopenias, ineffective and...
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External validation of a red cell-based blood prognostic score in patients with metastatic renal cell carcinoma treated with first-line immunotherapy combinations
Immunotherapy combinations with tyrosine-kinase inhibitors (TKIs) and immune checkpoint inhibitors (ICIs) had significantly improved outcomes of...
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Insecticide-treated net ownership, utilization and knowledge of malaria in children residing in Batoke–Limbe, Mount Cameroon area: effect on malariometric and haematological indices
BackgroundInsecticide-treated nets (ITNs) are the most widely used interventions for malaria control in Africa. The aim of this study was to assess...
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Evaluation of immunophenotypic alterations of peripheral blood lymphocytes and their sub-sets in uncomplicated P. Falciparum infection
BackgroundMalaria is a life-threatening parasitic disease typically transmitted through the bite of an infected Anopheles mosquito. There is ample...
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The role of immune-inflammatory markers in children with complicated and uncomplicated malaria in Enugu, Nigeria
BackgroundThere is currently insufficient data regarding immune parameters and relationship with severity of malaria infection in Enugu, Nigeria...
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An atlas of mitochondrial DNA genotype–phenotype associations in the UK Biobank
Mitochondrial DNA (mtDNA) variation in common diseases has been underexplored, partly due to a lack of genotype calling and quality-control...
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X-linked sideroblastic anaemia in a female fetus: a case report and a literature review
BackgroundX-linked sideroblastic anaemia (XLSA) is commonly due to mutations in the ALAS2 gene and predominantly affects hemizygous males....
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A novel variant of SLC4A1 for hereditary spherocytosis in a Chinese family: a case report and systematic review
BackgroundThe incidence of hereditary spherocytosis (HS) is approximately 1:2000 in the western population, while it is much lower in the Chinese...
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Development and validation of a machine learning-based nomogram for predicting HLA-B27 expression
BackgroundHLA-B27 positivity is normal in patients undergoing rheumatic diseases. The diagnosis of many diseases requires an HLA-B27 examination.
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