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Albendazole inhibits colon cancer progression and therapy resistance by targeting ubiquitin ligase RNF20
BackgroundThe repurposing of FDA-approved drugs for anti-cancer therapies is appealing due to their established safety profiles and pharmacokinetic...
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Albendazole Monotherapy for Pediatric Cystic Echinococcosis: A Case Series
BackgroundData regarding albendazole monotherapy for cystic echinococcosis (CE) are scarce, especially in children. We report our experience treating...
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Modeling and comparison of dissolution profiles for different brands of albendazole boluses
BackgroundAddressing critical veterinary drugs, especially drugs with solubility problems like albendazole, and their implications for therapeutic...
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Development and Pharmacokinetic Evaluation of Two Parenteral Formulations of Albendazole Using Prodrug and Cosolvent Approaches
Albendazole is a broad-spectrum anthelmintic drug used for parasitic infections. In addition, due to its mechanism of action, it has been studied as...
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Application potential of albendazole as an aquatic animal drug based on its safety, efficacy, and residue profiles
The number of available drugs for treating aquatic animals is insufficient, given the occurrence of a variety of parasites and difficulties in...
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Appraisal of Chitosan-Coated Lipid Nano-Combination with Miltefosine and Albendazole in the Treatment of Murine Trichinellosis: Experimental Study with Evaluation of Immunological and Immunohistochemical Parameters
PurposeResistance and adverse consequences of albendazole (ABZ) in treating trichinellosis urged demand for secure and effective new drugs. The...
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Phospholipid Complexation for Bioavailability Improvement of Albendazole: Preparation, Characterization and In Vivo Evaluation
The current study aimed to improve the poor solubility of albendazole (ABZ) by means of phospholipid complexation, hence to improve its oral...
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Saturation Solubility and Dissolution Property Improvement of Albendazole by Salt Formation Approach
PurposeAlbendazole belongs to BCS-II category whose systemic and local anthelmintic effectiveness is restricted due to its low water...
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Clinical tolerance and efficacy of anti-parasitic treatment with albendazole in patients with alveolar echinococcosis: long-term follow-up observation in 117 patients
Alveolar echinococcosis is the most severe worm disease primarily detected in the liver. This study aimed to determine the clinical tolerance and...
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MDR1 protein (ABC-C1) Over Expression in Giardia Intestinalis Incubated with Albendazole and Nitazoxanide
BackgroundGiardia intestinalis is a worldwide parasite. Drugs used for the treatment of giardiasis are metronidazole, albendazole and nitazoxanide....
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In vitro evaluation of albendazole-loaded nanostructured lipid carriers on Echinococcus granulosus microcysts and their prophylactic efficacy on experimental secondary hydatidosis
To enhance the therapeutic effects of albendazole (ABZ) on Echinococcus granulosus protoscoleces and metacestodes, ABZ-loaded nanostructured lipid...
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In vivo efficacy of combination therapy with albendazole and atovaquone against primary hydatid cysts in mice
Alveolar echinococcosis (AE) is caused by the larval stage of Echinococcus multilocularis . Chemotherapy for AE involves albendazole (ABZ), which has...
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Toxocarosis in a patient with autism spectrum disorder presenting with severe hypereosinophilia and acute respiratory distress: a case report
A boy with known autism spectrum disorder was transferred to our department due to a rapidly worsening respiratory situation. The patient’s history...
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Testing Albendazole Resistance in Fasciola hepatica
The egg development test is a useful in vitro tool to detect albendazole (ABZ) resistance in Fasciola hepatica. ABZ is the only flukicidal compound...
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The impact of β-glucan on the therapeutic outcome of experimental Trichinella spiralis infection
Trichinellosis is a cosmopolitan zoonosis that is caused mainly by Trichinella spiralis infection. The human disease ranges from mild to severe and...
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The Impact of Pulmonary Hydatid Cyst Rupture on COVID-19 Symptom Severity
BackgroundCo-infection with other microorganisms such as parasites in patients with COVID-19 can affect the clinical outcome and require prompt...
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First report of Dactylogyrus formosus from India: a case of co-existence with Paradactylogyrus catlaius causing mass mortality in Indian major carp, Catla catla
The family Dactylogyridae, known for its role as a frequent pathogen in Cyprinids, was identified in a case of mass mortality involving Catla catla ...
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Evaluation of the efficacy of albendazole sulfoxide (ABZ-SO)–loaded chitosan-PLGA nanoparticles in the treatment of cystic echinococcosis in laboratory mice
Albendazole is known as the drug of choice for medical treatment of cystic echinococcosis (CE). Albendazole sulfoxide (ABZ-SO), as the main active...
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Effect of Genotype and Sex of the Host on the Bioavailability of Novel Albendazole Microcrystals Based on Chitosan and Cellulose Derivatives
Albendazole (ABZ), an anthelmintic compound widely used in the treatment of systemic nematode infections, is included in the list of class II drugs...
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Gut microbiome of helminth-infected indigenous Malaysians is context dependent
BackgroundWhile microbiomes in industrialized societies are well characterized, indigenous populations with traditional lifestyles have microbiomes...
