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60 Result(s)
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Chapter and Conference Paper
Proofs and Refutations in Invariant-Based Programming
Invariant-based programming is a correct-by-construction approach to program development in which the invariants of a program are written before the actual code. Socos is an environment for gra...
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Article
Invariant diagrams with data refinement
Invariant based programming is an approach where we start to construct a program by first identifying the basic situations (pre- and post-conditions as well as invariants) that could aris...
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Article
A simple mass-action model for the eukaryotic heat shock response and its mathematical validation
The heat shock response is a primordial defense mechanism against cell stress and protein misfolding. It proceeds with the minimum number of mechanisms that any regulatory network must include, a stress-induce...
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Book
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Article
Structured derivations: a unified proof style for teaching mathematics
Structured derivations were introduced by Back and von Wright as an extension of the calculational proof style originally proposed by E. W. Dijkstra and his colleagues. Structured derivations added nested subd...
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Chapter and Conference Paper
Refinement Calculus as a Theory of Contracts (Invited Paper)
We describe a foundation for refinement calculus where pro- grams and systems are described as contracts, carried out by a collection of interacting agents. The contract states explicitly what the agents are a...
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Chapter and Conference Paper
Applying PVS Background Theories and Proof Strategies in Invariant Based Programming
Invariant Based Programming (IBP) is a formal method in which the invariants are developed before the code. IBP leads to programs that are correct by construction, provides a light formalism that...
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Article
Invariant based programming: basic approach and teaching experiences
Program verification is usually done by adding specifications and invariants to the program and then proving that the verification conditions are all true. This makes program verification an alternative to or ...
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Book
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Chapter
A New Mathematical Model for the Heat Shock Response
We present in this paper a novel molecular model for the gene regulatory network responsible for the eukaryotic heat shock response. Our model includes the temperature-induced protein misfolding, the chaperone...
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Chapter and Conference Paper
Computational Heuristics for Simplifying a Biological Model
Computational biomodelers adopt either of the following approaches: build rich, as complete as possible models in an effort to obtain very realistic models, or on the contrary, build as simple as possible mode...
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Chapter and Conference Paper
Control Strategies for the Regulation of the Eukaryotic Heat Shock Response
Elevated temperatures cause proteins in living cells to misfold. They start forming larger and larger aggregates that can eventually lead to the cell’s death. The heat shock response is an evolutionary well co...
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Chapter and Conference Paper
Testing and Verifying Invariant Based Programs in the SOCOS Environment
SOCOS is a prototype tool for constructing programs and reasoning about their correctness. It supports the invariant based programming methodology by providing a diagrammatic environment for specification, imp...
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Chapter and Conference Paper
Incremental Software Construction with Refinement Diagrams
We propose here a mathematical framework for incremental software construction and controlled software evolution. The framework allows incremental changes of a software system to be described on a high architectu...
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Chapter and Conference Paper
Invariant Based Programming
Program verification is usually done by adding specifications and invariants to the program and then proving that the verification conditions are all true. This makes program verification an alternative to or ...
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Chapter and Conference Paper
Using Stepwise Feature Introduction in Practice: An Experience Report
Stepwise Feature Introduction is an incremental method and software architecture for building object-oriented system in thin layers of functionality, and is based on the Refinement Calculus logical framework. ...
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Article
An algebraic treatment of procedure refinement to support mechanical verification
We introduce a new algebraic model for program variables, suitable for reasoning about recursive procedures with parameters and local variables in a mechanical verification setting. We give a predicate transfo...
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Chapter and Conference Paper
Software Development and Experimentation in an Academic Environment: The Gaudi Experience
In this article, we describe an approach to empirical software engineering based on a combined software factory and software laboratory. The software factory develops software required by an external customer ...
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Chapter and Conference Paper
Incremental Software Construction with Refinement Diagrams
We propose here a mathematical framework for incremental software construction and for controlled software evolution. The framework allows incremental changes of a software system to be described on a high archit...
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Chapter and Conference Paper
A Workbench to Experiment on New Model Engineering Applications
There are many di.erent tools that support, in one way or another, the Uni.ed Modeling Language (UML), but most of these tools are targeted to software developers. The System Modeling Workbench (SMW) [8] is a ...
