8 Result(s)
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Chapter and Conference Paper
Formal Methods for Checking the Consistency of Biological Models
Formal modeling approaches such as process algebras and Petri nets seek to provide insight into biological processes by using both symbolic and numerical methods to reveal the dynamics of the process under stu...
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Chapter
Translation from the Quantified Implicit Process Flow Abstraction in SBGN-PD Diagrams to Bio-PEPA Illustrated on the Cholesterol Pathway
For a long time biologists have used visual representations of biochemical networks to gain a quick overview of important structural properties. Recently SBGN, the Systems Biology Graphical Notation, has been ...
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Open Access This content is freely available online to anyone, anywhere at any time.
Article
Narrative-based computational modelling of the Gp130/JAK/STAT signalling pathway
Appropriately formulated quantitative computational models can support researchers in understanding the dynamic behaviour of biological pathways and support hypothesis formulation and selection by "in silico" ...
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Chapter and Conference Paper
Modelling Biological Clocks with Bio-PEPA: Stochasticity and Robustness for the Neurospora crassa Circadian Network
Circadian clocks are biochemical networks, present in nearly all living organisms, whose function is to regulate the expression of specific mRNAs and proteins to synchronise rhythms of metabolism, physiology a...
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Chapter
Qualitative and Quantitative Analysis of a Bio-PEPA Model of the Gp130/JAK/STAT Signalling Pathway
Computational modelling of complex biochemical systems has grown in importance over recent years as a tool for supporting biological studies. Consequently, several formal languages have been recently proposed ...
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Chapter
Process Calculi Abstractions for Biology
Several approaches have been proposed to model biological systems by means of the formal techniques and tools available in computer science. To mention just a few of them, some representations are inspired by ...
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Chapter and Conference Paper
An Automated Translation from a Narrative Language for Biological Modelling into Process Algebra
The aim of this work is twofold. First, we propose an high level textual modelling language, which is meant to be biologically intuitive and hence easily usable by life scientists in modelling intra-cellular s...
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Chapter and Conference Paper
Modeling Static Biological Compartments with Beta-binders
We investigate the modeling of biological systems with static compartments through Beta-binders, a recently developed process calculus. Biological entities are represented as bio-processes and the calculus is ...
