Magnetic Resonance Materials in Physics, Biology and Medicine
Volume 1 / 1993 - Volume 30 / 2017
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30,410 Result(s)
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Open Access This content is freely available online to anyone, anywhere at any time.
Article
HLA-check: evaluating HLA data from SNP information
The major histocompatibility complex (MHC) region of the human genome, and specifically the human leukocyte antigen (HLA) genes, play a major role in numerous human diseases. With the recent progress of sequen...
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Open Access This content is freely available online to anyone, anywhere at any time.
Article
Integrated genomic analysis of biological gene sets with applications in lung cancer prognosis
Burgeoning interest in integrative analyses has produced a rise in studies which incorporate data from multiple genomic platforms. Literature for conducting formal hypothesis testing on an integrative gene set...
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Open Access This content is freely available online to anyone, anywhere at any time.
Article
SegCorr a statistical procedure for the detection of genomic regions of correlated expression
Detecting local correlations in expression between neighboring genes along the genome has proved to be an effective strategy to identify possible causes of transcriptional deregulation in cancer. It has been s...
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Open Access This content is freely available online to anyone, anywhere at any time.
Article
Incorporating biological information in sparse principal component analysis with application to genomic data
Sparse principal component analysis (PCA) is a popular tool for dimensionality reduction, pattern recognition, and visualization of high dimensional data. It has been recognized that complex biological mechani...
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Journal
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Open Access This content is freely available online to anyone, anywhere at any time.
Article
Spatial pattern analysis of nuclear migration in remodelled muscles during Drosophila metamorphosis
Many human muscle wasting diseases are associated with abnormal nuclear localization. During metamorphosis in Drosophila melanogaster, multi-nucleated larval dorsal abdominal muscles either undergo cell death or ...
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Open Access This content is freely available online to anyone, anywhere at any time.
Article
ACE: an efficient and sensitive tool to detect insecticide resistance-associated mutations in insect acetylcholinesterase from RNA-Seq data
Insecticide resistance is a substantial problem in controlling agricultural and medical pests. Detecting target site mutations is crucial to manage insecticide resistance. Though PCR-based methods have been wi...
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Article
Variable slice thickness (VAST) EPI for the reduction of susceptibility artifacts in whole-brain GE-EPI at 7 Tesla
A new technique for 2D gradient-recalled echo echo-planar imaging (GE-EPI) termed ‘variable slice thickness’ (VAST) is proposed, which reduces signal losses caused by through-slice susceptibility artifacts, wh...
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Open Access This content is freely available online to anyone, anywhere at any time.
Article
LipidMatch: an automated workflow for rule-based lipid identification using untargeted high-resolution tandem mass spectrometry data
Lipids are ubiquitous and serve numerous biological functions; thus lipids have been shown to have great potential as candidates for elucidating biomarkers and pathway perturbations associated with disease. Me...
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Open Access This content is freely available online to anyone, anywhere at any time.
Article
Reliable Biomarker discovery from Metagenomic data via RegLRSD algorithm
Biomarker detection presents itself as a major means of translating biological data into clinical applications. Due to the recent advances in high throughput sequencing technologies, an increased number of met...
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Open Access This content is freely available online to anyone, anywhere at any time.
Article
Using the multi-objective optimization replica exchange Monte Carlo enhanced sampling method for protein–small molecule docking
In this study, we extended the replica exchange Monte Carlo (REMC) sampling method to protein–small molecule docking conformational prediction using RosettaLigand. In contrast to the traditional Monte Carlo (M...
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Article
Ab initio study of hydrogen bonding in the H3PO2 dimer and H3PO2–DMF complex
The molecular structures and H-bonding interactions in the phosphinic acid dimer and the complex of phosphinic acid with N,N-dimethylformamide (DMF) were investigated by density functional theory calculations at ...
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Journal
BioData Mining
Volume 1 / 2008 - Volume 10 / 2017
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Open Access This content is freely available online to anyone, anywhere at any time.
Article
epiACO - a method for identifying epistasis based on ant Colony optimization algorithm
Identifying epistasis or epistatic interactions, which refer to nonlinear interaction effects of single nucleotide polymorphisms (SNPs), is essential to understand disease susceptibility and to detect genetic ...
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Open Access This content is freely available online to anyone, anywhere at any time.
Article
Arete – candidate gene prioritization using biological network topology with additional evidence types
Refinement of candidate gene lists to select the most promising candidates for further experimental verification remains an essential step between high-throughput exploratory analysis and the discovery of spec...
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Open Access This content is freely available online to anyone, anywhere at any time.
Article
TnseqDiff: identification of conditionally essential genes in transposon sequencing studies
Tn-Seq is a high throughput technique for analysis of transposon mutant libraries to determine conditional essentiality of a gene under an experimental condition. A special feature of the Tn-seq data is that m...
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Article
Temperature dependence of 1H NMR chemical shifts and its influence on estimated metabolite concentrations
Temperature dependent chemical shifts of important brain metabolites measured by localised 1H MRS were investigated to test how the use of incorrect prior knowledge on chemical shifts impairs the quantification o...
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Open Access This content is freely available online to anyone, anywhere at any time.
Article
sgnesR: An R package for simulating gene expression data from an underlying real gene network structure considering delay parameters
sgnesR (Stochastic Gene Network Expression Simulator in R) is an R package that provides an interface to simulate gene expression data from a given gene network using the stochastic simulation algorithm (SSA)....
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Open Access This content is freely available online to anyone, anywhere at any time.
Article
An improved filtering algorithm for big read datasets and its application to single-cell assembly
For single-cell or metagenomic sequencing projects, it is necessary to sequence with a very high mean coverage in order to make sure that all parts of the sample DNA get covered by the reads produced. This lea...
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Open Access This content is freely available online to anyone, anywhere at any time.
Article
A novel method for constructing continuous intrinsic surfaces of nanoparticles
In recent years, the field of nanotechnology has become increasingly prevalent in the disciplines of science and engineering due to it’s abundance of application areas. Therefore, the ability to study and char...
