72,975 Result(s)
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Article
Influence of Ionization Source Conditions on the Gas-Phase Protomer Distribution of Anilinium and Related Cations
The gas-phase-ion generation technique and specific ion-source settings of a mass spectrometer influence heavily the protonation processes of molecules and the abundance ratio of the generated protomers. Hithe...
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Article
Observing Proton Transfer Reactions Inside the MALDI Plume: Experimental and Theoretical Insight into MALDI Gas-Phase Reactions
We evaluated the contribution of gas-phase in-plume proton transfer reactions to the formation of protonated and deprotonated molecules in the MALDI process. A split sample holder was used to separately deposi...
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Article
Functional Analysis of Differentially Expressed MicroRNAs Associated with Drought Stress in Diploid and Tetraploid Paulownia fortunei
MicroRNAs (miRNAs) are small, single-stranded, non-coding endogenous RNAs that play vital roles in the regulation of gene expression at the post-transcriptional level. Several studies of miRNAs in diploid and ...
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Article
Laser Desorption/Ionization Mass Spectrometric Imaging of Endogenous Lipids from Rat Brain Tissue Implanted with Silver Nanoparticles
Mass spectrometry imaging (MSI) of tissue implanted with silver nanoparticulate (AgNP) matrix generates reproducible imaging of lipids in rodent models of disease and injury. Gas-phase production and accelerat...
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Article
N3 and O2 Protonated Conformers of the Cytosine Mononucleotides Coexist in the Gas Phase
The gas-phase conformations of the protonated forms of the DNA and RNA cytosine mononucleotides, [pdCyd+H]+ and [pCyd+H]+, are examined by infrared multiple photon dissociation (IRMPD) action spectroscopy over th...
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Article
SnRK2 Homologs in Gossypium and GhSnRK2.6 Improved Salt Tolerance in Transgenic Upland Cotton and Arabidopsis
SnRK2s are a large family of plant-specific protein kinases, which play important roles in multiple abiotic stress responses in various plant species. But the family in Gossypium has not been well studied. Here, ...
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Article
Comparison of Ambient and Atmospheric Pressure Ion Sources for Cystic Fibrosis Exhaled Breath Condensate Ion Mobility-Mass Spectrometry Metabolomics
Cystic fibrosis (CF) is an autosomal recessive disorder caused by mutations in the gene that encodes the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The vast majority of the mortality i...
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Open Access This content is freely available online to anyone, anywhere at any time.
Article
A spiking neural network model of the midbrain superior colliculus that generates saccadic motor commands
Single-unit recordings suggest that the midbrain superior colliculus (SC) acts as an optimal controller for saccadic gaze shifts. The SC is proposed to be the site within the visuomotor system where the nonlin...
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Open Access This content is freely available online to anyone, anywhere at any time.
Article
Retrieving challenging vessel connections in retinal images by line co-occurrence statistics
Natural images contain often curvilinear structures, which might be disconnected, or partly occluded. Recovering the missing connection of disconnected structures is an open issue and needs appropriate geometr...
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Article
Bioinspired magnetic reception and multimodal sensing
Several animals use Earth’s magnetic field in concert with other sensor modes to accomplish navigational tasks ranging from local homing to continental scale migration. However, despite extensive research, ani...
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Article
Broad Separation of Isomeric Lipids by High-Resolution Differential Ion Mobility Spectrometry with Tandem Mass Spectrometry
Maturation of metabolomics has brought a deeper appreciation for the importance of isomeric identity of lipids to their biological role, mirroring that for proteoforms in proteomics. However, full characteriza...
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Article
MALDI Orbitrap Mass Spectrometry Profiling of Dysregulated Sulfoglycosphingolipids in Renal Cell Carcinoma Tissues
Matrix-assisted laser desorption/ionization coupled with Orbitrap mass spectrometry (MALDI-Orbitrap-MS) is used for the clinical study of patients with renal cell carcinoma (RCC), as the most common type of ki...
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Article
Sample Preparation of Corn Seed Tissue to Prevent Analyte Relocations for Mass Spectrometry Imaging
Corn seed tissue sections were prepared by the tape support method using an adhesive tape, and mass spectrometry imaging (MSI) was performed. The effect of heat generated during sample preparation was investig...
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Article
Limited capacity of working memory in unihemispheric random walks implies conceivable slow dispersal
Phenomenologically inspired by dolphins’ unihemispheric sleep, we introduce a minimal model for random walks with physiological memory. The physiological memory consists of long-term memory which includes unco...
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Article
DMSO Assisted Electrospray Ionization for the Detection of Small Peptide Hormones in Urine by Dilute-and-Shoot-Liquid-Chromatography-High Resolution Mass Spectrometry
The mobile phase additive (DMSO) has been described as a useful tool to enhance electrospray ionization (ESI) of peptides and proteins. So far, this technique has mainly been used in proteomic/peptide research...
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Article
Nominal Mass?
The current IUPAC-recommended definition of the term “nominal mass,” based on the most abundant naturally occurring stable isotope of an element, is flawed. We propose that Nominal mass should be defined as the s...
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Open Access This content is freely available online to anyone, anywhere at any time.
Article
Drought-Tolerant Brassica rapa Shows Rapid Expression of Gene Networks for General Stress Responses and Programmed Cell Death Under Simulated Drought Stress
Production of oilseed rape/canola (Brassica napus) is increasingly threatened by dry conditions while the demand for vegetable oil is increasing. Brassica rapa is a genetically diverse ancestor of B. napus, and i...
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Article
Ion Mobility Spectrometry - High Resolution LTQ-Orbitrap Mass Spectrometry for Analysis of Homemade Explosives
The detailed chemical characterization of homemade explosives (HMEs) and other chemicals that can mimic or mask the presence of explosives is important for understanding and improving the performance of commer...
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Article
An Electrospray Ionization Mass Spectrometry Study on the “In Vacuo” Hetero-Oligomers Formed by the Antimicrobial Peptides, Surfactin and Gramicidin S
It was previously observed that the lipopeptide surfactants in surfactin (Srf) have an antagonistic action towards the highly potent antimicrobial cyclodecapeptide, gramicidin S (GS). This study reports on som...
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Article
Molecular Dissection of a Genomic Region Governing Root Traits Associated with Drought Tolerance Employing a Combinatorial Approach of QTL Mapping and RNA-seq in Rice
Drought is considered as one of the major obstacles for progressive yield enhancement and stability in rice, especially in rain-fed conditions. Being a complex trait, drought is regulated by numerous quantitat...
