50 Result(s)

Chapter and Conference Paper

Quasi-opportunistic Supercomputing in Grid Environments

The ultimate vision of grid computing are virtual supercomputers of unprecedented power, through utilization of geographically dispersed distributively owned resources. Despite the overwhelming success of grid...

Valentin Kravtsov, David Carmeli… in Algorithms and Architectures for Parallel … (2008)

Chapter

Introduction to Genomic and Proteomic Data Analysis

Genomics can be broadly defined as the systematic study of genes, their functions, and their interactions. Analogously, proteomics is the study of proteins, protein complexes, their localizatio...

Daniel Berrar, Martin Granzow… in Fundamentals of Data Mining in Genomics an… (2007)

Chapter and Conference Paper

GetItFull – A Tool for Downloading and Pre-processing Full-Text Journal Articles

Automated analysis of full-text life science research articles and technical documents is becoming increasingly important. In contrast to abstracts, accessing and processing full-text is considerably more complex...

Jeyakumar Natarajan, Cliff Haines… in Knowledge Discovery in Life Science Litera… (2006)

Chapter and Conference Paper

Markov Modeling of Conformational Kinetics of Cardiac Ion Channel Proteins

Markov modeling of conformational kinetics of cardiac ion channels is a prospective means to correlate the molecular defects of channel proteins to their electrophysiological dysfunction. However, both the ide...

Chong Wang, Antje Krause, Chris Nugent… in Biological and Medical Data Analysis (2006)

Article

HealthGrid – Bridging Life Science and Information Technology

Chun-Hsi Huang, Vincenzo Lanza… in Journal of Clinical Monitoring and Computi… (2005)

Article

Towards Data Warehousing and Mining of Protein Unfolding Simulation Data

Objectives. The prediction of protein structure and the precise understanding of protein folding and unfolding processes remains one of the greatest challenges in structural biology and bioinformatics. Computer s...

Daniel Berrar, Frederic Stahl, Candida Silva… in Journal of Clinical Monitoring and Computi… (2005)

Article

Reverse-Engineering Gene-Regulatory Networks using Evolutionary Algorithms and Grid Computing

Objective. Living organisms regulate the expression of genes using complex interactions of transcription factors, messenger RNA and active protein products. Due to their complexity, gene-regulatory networks are n...

Martin Swain, Thomas Hunniford… in Journal of Clinical Monitoring and Computi… (2005)

Chapter and Conference Paper

A Grid Infrastructure for Text Mining of Full Text Articles and Creation of a Knowledge Base of Gene Relations

We demonstrate the application of a grid infrastructure for conducting text mining over distributed data and computational resources. The approach is based on using LexiQuest Mine, a text mining workbench, in ...

Jeyakumar Natarajan, Niranjan Mulay… in Biological and Medical Data Analysis (2005)

Chapter and Conference Paper

Focal Activity in Simulated LQT2 Models at Rapid Ventricular Pacing: Analysis of Cardiac Electrical Activity Using Grid-Based Computation

This study investigated the involvement of ventricular focal activity and dispersion of repolarization in LQT2 models at rapid rates. The Luo-Rudy dynamic model was used to simulate ventricular tissues. LQT2 s...

Chong Wang, Antje Krause, Chris Nugent… in Biological and Medical Data Analysis (2005)

Chapter

Integration of Microarray Data for a Comparative Study of Classifiers and Identification of Marker Genes

Novel diagnostic tools promise the development of patient-tailored cancer treatment. However, one major step towards individualized therapy is to use a combination of various data sources, e.g. transcriptomic,...

Daniel Berrar, Brian Sturgeon, Ian Bradbury… in Methods of Microarray Data Analysis (2005)