34 Result(s)
-
Open Access This content is freely available online to anyone, anywhere at any time.
Article
Analysis of feedback loops and robustness in network evolution based on Boolean models
Many biological networks such as protein-protein interaction networks, signaling networks, and metabolic networks have topological characteristics of a scale-free degree distribution. Preferential attachment h...
-
Open Access This content is freely available online to anyone, anywhere at any time.
Article
Investigations into the relationship between feedback loops and functional importance of a signal transduction network based on Boolean network modeling
A number of studies on biological networks have been carried out to unravel the topological characteristics that can explain the functional importance of network nodes. For instance, connectivity, clustering c...
-
Article
The effect of tripeptide-copper complex on human hair growth in vitro
The tripeptide-copper complex, described as a growth factor for various kinds of differentiated cells, stimulates the proliferation of dermal fibroblasts and elevates the production of vascular endothelial gro...
-
Article
Expression of androgen and estrogen receptors in human scalp mesenchymal cells in vitro
The expression levels of sex hormone receptors were identified to be different in human mesenchymal cells [dermal papilla cell (DPC), dermal sheath cell (DSC), dermal fibroblast and (DF)] from occipital scalps...
-
Open Access This content is freely available online to anyone, anywhere at any time.
Article
Least-squares methods for identifying biochemical regulatory networks from noisy measurements
We consider the problem of identifying the dynamic interactions in biochemical networks from noisy experimental data. Typically, approaches for solving this problem make use of an estimation algorithm such as ...
-
Article
Human hair growth ex vivo is correlated with in vivo hair growth: selective categorization of hair follicles for more reliable hair follicle organ culture
Of the numerous assays used to assess hair growth, hair follicle organ culture model is one of the most popular and powerful in vitro systems. Changes in hair growth are commonly employed as a measurement of f...
-
Chapter and Conference Paper
Identification of Gene Interaction Networks Based on Evolutionary Computation
This paper investigates applying a genetic algorithm and an evolutionary programming for identification of gene interaction networks from gene expression data. To this end, we employ recurrent neural networks ...
-
Article
The effects of epidermal keratinocytes and dermal fibroblasts on the formation of cutaneous basement membrane in three-dimensional culture systems
The cutaneous basement membrane (BM) plays an important role in normal and pathological conditions. However, few studies have addressed the formation of the cutaneous BM using three-dimensional culture systems...
-
Chapter and Conference Paper
How to Synthesize an Optimized Genetic λ-Switching System? A System-Theoretic Approach Based on SQP
The concept of gene regulation has been investigated by biologists for several decades and has led to the concept of gene regulatory circuits and biological switches. There have been several theoretical approa...
-
Chapter and Conference Paper
Simulation Sudy of the TNFα Mediated NF-κB Signaling Pathway
Tumor necrosis factor α (TNFα) is a potent proinflammatory cytokine that plays an important role in immunity and inflammation, in the control of cell proliferation, differentiation and apoptosis. This paper pr...
-
Article
Fibroblasts play a stimulatory role in keratinocyte proliferation but an inhibitory role in melanocyte growth and pigmentation in a skin equivalent system from skin type IV
-
Chapter and Conference Paper
Fuzzy Clustering of Short Time-Series and Unevenly Distributed Sampling Points
This paper proposes a new algorithm in the fuzzy-c-means family, which is designed to cluster time-series and is particularly suited for short time-series and those with unevenly spaced sampling points. Short tim...
-
Article
Vitamin D receptor genotypes are not associated with clinical response to calcipotriol in Korean psoriasis patients
Conflicting results have been reported on the association between BsmI restriction fragment length polymorphism (RFLP) at the vitamin D receptor gene (VDR) locus and the clinical response of psoriasis patients t...
-
Article
Human oral buccal mucosa reconstructed on dermal substrates: a model for oral epithelial differentiation
