24 Result(s)

within Hiroki Yokota

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    Article

    Osteogenic potentials with joint-loading modality

    Osteogenic potentials with a novel joint-loading modality were examined, using mouse ulnae as a model system. Load-induced deformation of rigid bone is known to generate interstitial fluid flow and stimulate o...

    Hiroki Yokota, Shigeo M. Tanaka in Journal of Bone and Mineral Metabolism (2005)

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    Article

    Osteoblast Responses One Hour After Load-Induced Fluid Flow in a Three-Dimensional Porous Matrix

    When bone is loaded, substrate strain is generated by the external force and this strain induces fluid flow that creates fluid shear stress on bone cells. Our current understanding of load-driven gene regulati...

    Shigeo M. Tanaka, Hui B. Sun, Ryan K. Roeder… in Calcified Tissue International (2005)

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    Article

    Model-Based Analysis of Matrix Metalloproteinase Expression Under Mechanical Shear

    We report the development of a model-based analysis for identification of the role of transcription factor (TF) binding motifs. A nonlinear mathematical model was formulated to establish the quantitative relat...

    Hui Bin Sun, Yunlong Liu, Lei Qian, Hiroki Yokota in Annals of Biomedical Engineering (2003)

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    Article

    Correlated Positioning of Homologous Chromosomes in Daughter Fibroblast Cells

    A new method of analyzing chromosome segregation in pairs of daughter human fibroblasts revealed that the positioning of chromosomes in daughter nuclei was closely correlated with their relative positions duri...

    Hui Bin Sun, Hiroki Yokota in Chromosome Research (1999)

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