Macromolecular crystallography and medicine

  • W. G. J. Hol
  • C. L. M. J. Verlinde
Reference work entry
Part of the International Tables for Crystallography book series (IUCR, volume F)


Macromolecular crystallography is discussed in terms of its impact on medicine, and selected examples of protein structures of medical relevance are provided. The application of crystallography to the study of genetic diseases is covered, as well as the role of crystallography in the development of novel pharmaceuticals. This chapter is also available as HTML from the International Tables Online site hosted by the IUCr.


Dihydrofolate Reductase Triosephosphate Isomerase Trypanosoma Brucei Purine Nucleoside Phosphorylase Maple Syrup Urine Disease 
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Copyright information

© International Union of Crystallography 2006

Authors and Affiliations

  • W. G. J. Hol
  • C. L. M. J. Verlinde

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