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Tissue-Engineering Bladder Augmentation

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Handbook of Neurourology

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Abstract

The accumulated knowledge of bladder histology and function as well as the progress in tissue-engineering technology has promoted the development of bladder regeneration. Tissue-engineering technology for bladder augmentation or regeneration holds strong potential in patients with neurogenic bladder, who develop renal impairment, by decreasing surgical time and reducing complications compared with conventional enterocystoplasty. Tissue-engineering technology could provide novel treatment options for bladder augmentation by regenerating epithelia and muscle using a variety of biomaterial scaffolds, along with autologous or allogeneic cells and growth factors. This approach might lead to the regeneration of partial bladder tissue or construction of a neo-bladder. This chapter reviewed the development for this field.

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  1. Department of Urology and Department of Neurourology, China Rehabilitation Research Center, China Rehabilitation Science Institute, Capital Medical University, Beijing, China

    Limin Liao

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  1. Department of Urology Department of Neurourology, China Rehabiliation Research Center China Rehabilitation Science InstituteCapital Medical University, Beijing, China

    Limin Liao

  2. Department of Urology, Medical University Innsbruck, University Hospital, Innsbruck, Austria

    Helmut Madersbacher

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Liao, L. (2023). Tissue-Engineering Bladder Augmentation. In: Liao, L., Madersbacher, H. (eds) Handbook of Neurourology. Springer, Singapore. https://doi.org/10.1007/978-981-99-1659-7_45

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