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Mental Health and Cardiovascular Disease Risk in Refugees

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Handbook of Psychocardiology
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Abstract

In 2013 there were 51.2 million persons worldwide who had been forcibly displaced as a result of persecution, conflict, generalized violence, or human rights violations. 16.7 million persons, half of whom were children, were refugees. More than 80 % were living in refugee camps and other generally temporary although often long-lasting arrangements, in developing countries. From this massive population, only 98,000 were resettled in refugee-receiving countries. The prevalence of mental disorders, particularly post-traumatic stress disorder, depression, and anxiety, is greater in refugees than in non-refugees, although prevalence estimates vary greatly. As well as having poorer mental health, refugees are also more likely than non-refugee immigrants or host populations to experience poorer physical health, higher all-cause mortality, and higher cardiovascular mortality. Although the severe and persistent stress that is a central element of refugee experience is probably an independent risk factor for cardiovascular disease, it seems likely that the higher cardiovascular risk is mediated by mental disorders, such as post-traumatic stress disorder and depression, which are common in refugees and are clearly associated with increased cardiovascular risk. In addition, refugees are less likely to have access to effective mental health and general health services, resulting in further avoidable risk of cardiovascular morbidity and mortality.

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References

  • Al Kasseh, A. S., Zaki, N. M., Aljeesh, Y. I., & Soon, L. K. (2014). Risk factors of gestational diabetes mellitus in the refugee population in Gaza strip: A case-control study. Eastern Mediterranean Health Journal, 19(Suppl 3), S12–S18.

    Google Scholar 

  • Asgary, R., Emery, E., & Wong, M. (2013). Systematic review of prevention and management strategies for the consequences of gender-based violence in refugee settings. International Health, 5(2), 85–91.

    Article  PubMed  Google Scholar 

  • Bellamy, K., Ostini, R., Martini, N., & Kairuz, T. (2015). Access to medication and pharmacy services for resettled refugees: A systematic review. Australian Journal of Primary Health, 21(3). doi:10.1071/PY14121.

    Google Scholar 

  • Bigger, J. T. & Glassman, A. H. (2010). The American Heart Association science advisory on depression and coronary heart disease: an exploration of the issues raised. Cleve Clin J Med, 77(Suppl 3), S12–19.

    Google Scholar 

  • Boscarino, J. A. (2006a). Posttraumatic stress disorder and mortality among U.S. Army veterans 30 years after military service. Annals of Epidemiology, 16(4), 248–256.

    Article  PubMed  Google Scholar 

  • Boscarino, J. A. (2006b). External-cause mortality after psychologic trauma: The effects of stress exposure and predisposition. Comprehensive Psychiatry, 47(6), 503–514.

    Article  PubMed  Google Scholar 

  • Bouzinova, E. V., Wiborg, O., Aalkjaer, C., & Matchkov, V. V. (2014). The role of peripheral vascular resistance for the association between major depression and cardiovascular disease. Journal of Cardiovascular Pharmacology, 65(4), 299–307.

    Google Scholar 

  • Callaghan, R. C., & Khizar, A. (2010). The incidence of cardiovascular morbidity among patients with bipolar disorder: A population-based longitudinal study in Ontario, Canada. Journal of Affective Disorders, 122(1–2), 118–123.

    Article  PubMed  Google Scholar 

  • Callaghan, R. C., Boire, M. D., Lazo, R. G., McKenzie, K., & Cohn, T. (2009). Schizophrenia and the incidence of cardiovascular morbidity: A population-based longitudinal study in Ontario, Canada. Schizophrenia Research, 115(2–3), 325–332.

    Article  PubMed  Google Scholar 

  • Carney, R. M., Freedland, K. E., Stein, P. K., Skala, J. A., Hoffman, P., & Jaffe, A. S. (2000). Change in heart rate and heart rate variability during treatment for depression in patients with coronary heart disease. Psychosomatic Medicine, 62(5), 639–647.

    Article  PubMed  Google Scholar 

  • Carney, R. M., Blumenthal, J. A., Stein, P. K., Watkins, L., Catellier, D., Berkman, L. F., Czajkowski, S. M., O’Connor, C., Stone, P. H., & Freedland, K. E. (2001). Depression, heart rate variability, and acute myocardial infarction. Circulation, 104(17), 2024–2028.

    Article  PubMed  Google Scholar 

  • Carney, R. M., Blumenthal, J. A., Freedland, K. E., Stein, P. K., Howells, W. B., Berkman, L. F., Watkins, L. L., Czajkowski, S. M., Hayano, J., Domitrovich, P. P., & Jaffe, A. S. (2005). Low heart rate variability and the effect of depression on post-myocardial infarction mortality. Archives of Internal Medicine, 165(13), 1486–1491.

    Article  PubMed  Google Scholar 

  • Clark, R. C., & Mytton, J. (2007). Estimating infectious disease in UK asylum seekers and refugees: A systematic review of prevalence studies. Journal of Public Health (Oxford, England), 29(4), 420–428.

    Article  Google Scholar 

  • Colucci, E., Minas, H., Szwarc, J., Guerra, C., & Paxton, G. (2015). In or out? Barriers and facilitators to refugee-background young people accessing mental health services. Transcultural Psychiatry, 52, 766–790.

    Article  PubMed  Google Scholar 

  • Drummond, P. D., Mizan, A., Burgoyne, A., & Wright, B. (2011). Knowledge of cardiovascular risk factors in West African refugee women living in Western Australia. Journal of Immigrant and Minority Health, 13(1), 140–148.

    Article  PubMed  Google Scholar 

  • Fernandez-San-Martin, M. I., Martin-Lopez, L. M., Masa-Font, R., Olona-Tabuena, N., Roman, Y., Martin-Royo, J., Oller-Canet, S., Gonzalez-Tejon, S., San-Emeterio, L., Barroso-Garcia, A., Vinas-Cabrera, L., & Flores-Mateo, G. (2014). The effectiveness of lifestyle interventions to reduce cardiovascular risk in patients with severe mental disorders: Meta-analysis of intervention studies. Community Mental Health Journal, 50(1), 81–95.

    Article  PubMed  Google Scholar 

  • Gehi, A., Mangano, D., Pipkin, S., Browner, W. S., & Whooley, M. A. (2005). Depression and heart rate variability in patients with stable coronary heart disease: Findings from the heart and soul study. Archives of General Psychiatry, 62(6), 661–666.

    Article  PubMed  PubMed Central  Google Scholar 

  • Gierisch, J. M., Nieuwsma, J. A., Bradford, D. W., Wilder, C. M., Mann-Wrobel, M. C., McBroom, A. J., Hasselblad, V., & Williams, J. W., Jr. (2014). Pharmacologic and behavioral interventions to improve cardiovascular risk factors in adults with serious mental illness: A systematic review and meta-analysis. The Journal of Clinical Psychiatry, 75(5), e424–e440.

    Article  PubMed  Google Scholar 

  • Halaris, A. (2013). Co-morbidity between cardiovascular pathology and depression: Role of inflammation. Modern Trends in Pharmacopsychiatry, 28, 144–161.

    Article  PubMed  Google Scholar 

  • Healy, D., Le Noury, J., Harris, M., Butt, M., Linden, S., Whitaker, C., Zou, L., & Roberts, A. P. (2012). Mortality in schizophrenia and related psychoses: Data from two cohorts, 1875–1924 and 1994–2010. BMJ Open, 2(5), e001810.

    Article  PubMed  PubMed Central  Google Scholar 

  • Hollander, A. C. (2013). Social inequalities in mental health and mortality among refugees and other immigrants to Sweden – Epidemiological studies of register data. Global Health Action, 6, 21059.

    Article  PubMed  Google Scholar 

  • Hollander, A. C., Bruce, D., Ekberg, J., Burstrom, B., Borrell, C., & Ekblad, S. (2012). Longitudinal study of mortality among refugees in Sweden. International Journal of Epidemiology, 41(4), 1153–1161.

    Article  PubMed  Google Scholar 

  • Hollifield, M., Warner, T. D., Lian, N., Krakow, B., Jenkins, J. H., Kesler, J., Stevenson, J., & Westermeyer, J. (2002). Measuring trauma and health status in refugees: A critical review. JAMA, 288(5), 611–621.

    Article  PubMed  Google Scholar 

  • Huffman, J. C., Celano, C. M., Beach, S. R., Motiwala, S. R., & Januzzi, J. L. (2013). Depression and cardiac disease: Epidemiology, mechanisms, and diagnosis. Cardiovascular Psychiatry and Neurology, 2013, 695925.

    Article  PubMed  PubMed Central  Google Scholar 

  • Kessler, R. C., Angermeyer, M., Anthony, J. C., De Graaf, R., Demyttenaere, K., Gasquet, I., de Girolamo, G., Gluzman, S., Gureje, O., Haro, J. M., Kawakami, N., Karam, A., Levinson, D., Medina Mora, M. E., Oakley Browne, M. A., Posada-Villa, J., Stein, D. J., Adley Tsang, C. H., Aguilar-Gaxiola, S., Alonso, J., Lee, S., Heeringa, S., Pennell, B. E., Berglund, P., Gruber, M. J., Petukhova, M., Chatterji, S., & Ustun, T. B. (2007). Lifetime prevalence and age-of-onset distributions of mental disorders in the World Health Organization’s World Mental Health Survey Initiative. World Psychiatry, 6(3), 168–176.

    PubMed  PubMed Central  Google Scholar 

  • Lichtman, J. H., Froelicher, E. S., Blumenthal, J. A., Carney, R. M., Doering, L. V., Frasure-Smith, N., Freedland, K. E., Jaffe, A. S., Leifheit-Limson, E. C., Sheps, D. S., Vaccarino, V., Wulsin, L., American Heart Association Statistics Committee of the Council on Epidemiology and Prevention, & Council on Cardiovascular and Stroke Nursing. (2014). Depression as a risk factor for poor prognosis among patients with acute coronary syndrome: Systematic review and recommendations: A scientific statement from the American Heart Association. Circulation, 129(12), 1350–1369.

    Article  PubMed  Google Scholar 

  • Lindert, J., Ehrenstein, O. S., Priebe, S., Mielck, A., & Brahler, E. (2009). Depression and anxiety in labor migrants and refugees – A systematic review and meta-analysis. Social Science & Medicine, 69(2), 246–257.

    Article  Google Scholar 

  • MacDuff, S., Grodin, M. A., & Gardiner, P. (2011). The use of complementary and alternative medicine among refugees: A systematic review. Journal of Immigrant and Minority Health, 13(3), 585–599.

    Article  PubMed  Google Scholar 

  • Martens, E. J., Nyklicek, I., Szabo, B. M., & Kupper, N. (2008). Depression and anxiety as predictors of heart rate variability after myocardial infarction. Psychological Medicine, 38(3), 375–383.

    Article  PubMed  Google Scholar 

  • Minas, H., Kakuma, R., Too, L. S., Vayani, H., Orapeleng, S., Prasad-Ildes, R., Turner, G., Procter, N., & Oehm, D. (2013). Mental health research and evaluation in multicultural Australia: Developing a culture of inclusion. International Journal of Mental Health Systems, 7(1), 23.

    Article  PubMed  PubMed Central  Google Scholar 

  • Nielsen, T. J., Vestergaard, M., Christensen, B., Christensen, K. S., & Larsen, K. K. (2013). Mental health status and risk of new cardiovascular events or death in patients with myocardial infarction: A population-based cohort study. British Medical Journal Open, 3(8):e003045

    Google Scholar 

  • Porter, M., & Haslam, N. (2005). Predisplacement and postdisplacement factors associated with mental health of refugees and internally displaced persons: A meta-analysis. JAMA, 294(5), 602–612.

    Article  PubMed  Google Scholar 

  • Renzaho, A. M., Nowson, C., Kaur, A., Halliday, J. A., Fong, D., & Desilva, J. (2011). Prevalence of vitamin D insufficiency and risk factors for type 2 diabetes and cardiovascular disease among African migrant and refugee adults in Melbourne: A pilot study. Asia Pacific Journal of Clinical Nutrition, 20(3), 397–403.

    PubMed  Google Scholar 

  • Renzaho, A. M., Bilal, P., & Marks, G. C. (2014). Obesity, type 2 diabetes and high blood pressure amongst recently arrived Sudanese refugees in Queensland, Australia. Journal of Immigrant and Minority Health, 16(1), 86–94.

    Article  PubMed  Google Scholar 

  • Ringen, P. A., Engh, J. A., Birkenaes, A. B., Dieset, I., & Andreassen, O. A. (2014). Increased mortality in schizophrenia due to cardiovascular disease – A non-systematic review of epidemiology, possible causes, and interventions. Frontiers in Psychiatry, 5, 137.

    Article  PubMed  PubMed Central  Google Scholar 

  • Robinson, R. G., Spalletta, G., Jorge, R. E., Bassi, A., Colivicchi, F., Ripa, A., & Caltagirone, C. (2008). Decreased heart rate variability is associated with poststroke depression. The American Journal of Geriatric Psychiatry, 16(11), 867–873.

    Article  PubMed  PubMed Central  Google Scholar 

  • Rossi, C., Shrier, I., Marshall, L., Cnossen, S., Schwartzman, K., Klein, M. B., Schwarzer, G., & Greenaway, C. (2012). Seroprevalence of chronic hepatitis B virus infection and prior immunity in immigrants and refugees: A systematic review and meta-analysis. PloS One, 7(9), e44611.

    Article  PubMed  PubMed Central  Google Scholar 

  • Steel, Z., C. Marnane, C. Iranpour, T. Chey, J. W. Jackson, V. Patel & D. Silove (2014). The global prevalence of common mental disorders: a systematic review and meta-analysis 1980–2013. Int J Epidemiol, 43(2), 476–493.

    Google Scholar 

  • Steel, Z., Chey, T., Silove, D., Marnane, C., Bryant, R. A., & van Ommeren, M. (2009). Association of torture and other potentially traumatic events with mental health outcomes among populations exposed to mass conflict and displacement: A systematic review and meta-analysis. JAMA, 302(5), 537–549.

    Article  PubMed  Google Scholar 

  • Stein, P. K., Carney, R. M., Freedland, K. E., Skala, J. A., Jaffe, A. S., Kleiger, R. E., & Rottman, J. N. (2000). Severe depression is associated with markedly reduced heart rate variability in patients with stable coronary heart disease. Journal of Psychosomatic Research, 48(4–5), 493–500.

    Article  PubMed  Google Scholar 

  • Sundquist, J., Cmelic-Eng, M., & Johansson, S. E. (1999). Body mass index and distribution of body fat in female Bosnian refugees – A study in primary health care. Public Health, 113(2), 89–93.

    Article  PubMed  Google Scholar 

  • Sundquist, J., Hagstromer, M., Johansson, S. E., & Sundquist, K. (2010). Effect of a primary health-care-based controlled trial for cardiorespiratory fitness in refugee women. BMC Family Practice, 11, 55.

    Article  PubMed  PubMed Central  Google Scholar 

  • Thombs, B. D., M. Roseman, J. C. Coyne, P. de Jonge, V. C. Delisle, E. Arthurs, B. Levis & R. C. Ziegelstein (2013). Does evidence support the American Heart Association’s recommendation to screen patients for depression in cardiovascular care? An updated systematic review. PLoS One 8(1):e52654.

    Google Scholar 

  • Tomlinson, L. A., & Cockcroft, J. R. (2011). Post-traumatic stress disorder: Breaking hearts. European Heart Journal, 32(6), 668–669.

    Article  PubMed  Google Scholar 

  • United Nations High Commissioner for Refugees. (2014). War’s human cost: UNHCR Global Trends 2013. Geneva: United Nations High Commissioner for Refugees.

    Google Scholar 

  • Vu, A., Adam, A., Wirtz, A., Pham, K., Rubenstein, L., Glass, N., Beyrer, C., & Singh, S. (2014). The prevalence of sexual violence among female refugees in complex humanitarian emergencies: A systematic review and meta-analysis. PLOS Currents Disasters, 6 Edition 1. doi: 10.1371/currents.dis.835f10778fd80ae031aac12d3b533ca7

    Google Scholar 

  • Willard, C. L., Rabin, M., & Lawless, M. (2014). The prevalence of torture and associated symptoms in United States Iraqi refugees. Journal of Immigrant and Minority Health, 16(6), 1069–1076.

    Article  PubMed  Google Scholar 

  • Yun, K., Hebrank, K., Graber, L. K., Sullivan, M. C., Chen, I., & Gupta, J. (2012). High prevalence of chronic non-communicable conditions among adult refugees: Implications for practice and policy. Journal of Community Health, 37(5), 1110–1118.

    Article  PubMed  Google Scholar 

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Correspondence to Harry Minas .

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Minas, H. (2016). Mental Health and Cardiovascular Disease Risk in Refugees. In: Alvarenga, M., Byrne, D. (eds) Handbook of Psychocardiology. Springer, Singapore. https://doi.org/10.1007/978-981-287-206-7_34

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