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Nanobiodevice for Nucleic Acid Sensing

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Handbook of Chemical Biology of Nucleic Acids

Abstract

Nanobiodevices, a technology characterized by engineered nanostructures, have attracted extensive interest as a new generation bioanalytical tool that allows accessing the information contained in nucleic acids. Distinct properties of nanobiodevice technologies have shown great promise in improvements in sensitivity, speed, and accuracy for nucleic acid analysis, providing a cutting-edge analytical tool to facilitate the analysis of nucleic acid in biomedical applications. In this chapter, an overview of nanobiodevices and how this emergent technology can be combined with other analytical approaches for addressing different challenges in biomedical applications will be provided. The recent advances in nanobiodevice for nucleic acid analysis will be highlighted in the following categories: (i) nanobiodevice for preparation of nucleic acid and (ii) nanobiodevice for detection of nucleic acid.

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Correspondence to Yoshinobu Baba .

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Takahashi, H., Yasui, T., Baba, Y. (2022). Nanobiodevice for Nucleic Acid Sensing. In: Sugimoto, N. (eds) Handbook of Chemical Biology of Nucleic Acids. Springer, Singapore. https://doi.org/10.1007/978-981-16-1313-5_55-1

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