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Handbook of Dietary Phytochemicals pp 1–22Cite as

Dietary Xanthones

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Abstract

Xanthones, polyphenolic compounds, are one of the most important classes in natural products, as they exhibit variety of pharmacological and health benefits, i.e., anti-obesity, antidiabetic, antioxidant, anti-Alzheimer, anti-inflammatory, and anticancer. Xanthones can be found in higher plants that are used as food sources, for example, Garcinia mangostana L. (the queen of fruits, mangosteen), a tropical fruit with reddish-purple pericarp that ca. 80% of it consists of xanthones. α-, β-, and γ-Mangostin are the major xanthones present in mangosteen that exhibit potential pharmacological activities. Mangosteen is used as popular food in beverages and in other health products. Also, it is traditionally used as a remedy in treating wounds, inflammation, and bacterial infections. Here in in this chapter, we draw the attention to xanthone compounds present in mangosteen showing their bioactivity and benefits on health, biosynthesis, drug discovery, registered patents, and physicochemical property space.

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Acknowledgments

H.R. El-Seedi is very grateful to the Swedish Research links grant 2016-05885 (VR for the years 2017–2019) for the generous financial support and to Jiangsu University, China, and Al-Rayan Colleges, Medina, Saudi Arabia, for Adjunct and Consultant Professor Fellowships, respectively; Mohamed A. Farag acknowledges the funding received from the Alexander von Humboldt Foundation, Germany.

Author information

Authors and Affiliations

  1. Pharmacognosy Group, Department of Medicinal Chemistry, Uppsala University, Biomedical Centre, Uppsala, Sweden

    Hesham R. El-Seedi & Aida Abd El-Wahed

  2. International Research Center for Food Nutrition and Safety, Jiangsu University, Zhenjiang, China

    Hesham R. El-Seedi

  3. Department of Chemistry, Faculty of Science, Menoufia University, Shebin El-Kom, Egypt

    Hesham R. El-Seedi, Omar M. Khattab & Aida Abd El-Wahed

  4. Al-Rayan Research and Innovation Center, Al-Rayan Colleges, Medina, Saudi Arabia

    Hesham R. El-Seedi & Mohammed F. Halabi

  5. Department of Pharmacognosy, Faculty of Pharmacy, Menoufia University, Shebin El-Kom, Egypt

    Mohamed A. Salem

  6. Pharmacognosy Department, Faculty of Pharmacy, The British University in Egypt (BUE), Cairo, Egypt

    Dina M. El-Kersh

  7. Department of Molecular Biosciences, Stockholm University, The Wenner-Gren Institute, Stockholm, Sweden

    Shaden A. M. Khalifa

  8. Department of Chemistry, Quaid-i-Azam University, Islamabad, Pakistan

    Aamer Saeed

  9. Department of Zoology, Science College, King Saud University, Riyadh, Saudi Arabia

    Mohamed M. Abdel-Daim

  10. Pharmacology Department, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, Egypt

    Mohamed M. Abdel-Daim

  11. Centre of Excellence in Bionanoscience Research, King Abdulaziz University (KAU), Jeddah, Saudi Arabia

    Nahid H. Hajrah

  12. Biotechnology Research Group, Department of Biological Sciences, Faculty of Science, King Abdulaziz University (KAU), Jeddah, Saudi Arabia

    Nahid H. Hajrah

  13. Medicinal and Natural Products Chemistry Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

    Amir R. Jassbi

  14. H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan

    Syed G. Musharraf

  15. Pharmacognosy Department, College of Pharmacy, Cairo University, Cairo, Egypt

    Mohamed A. Farag

  16. Department of Chemistry, School of Sciences & Engineering, The American University in Cairo, New Cairo, Egypt

    Mohamed A. Farag

  17. Department of Pharmaceutical Biology/Pharmacognosy, Institute of Pharmacy, University of HalleWittenberg, Halle (Saale), Germany

    Muaaz M. Alajlani

  18. Pharmacognosy Group, Department of Medicinal Chemistry, Uppsala University, Biomedical centre, Uppsala, Sweden

    Omar M. Khattab

Authors
  1. Hesham R. El-Seedi
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  2. Mohamed A. Salem
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  3. Omar M. Khattab
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  7. Aamer Saeed
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  11. Mohammed F. Halabi
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  14. Mohamed A. Farag
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Correspondence to Hesham R. El-Seedi or Mohamed A. Farag .

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Editors and Affiliations

  1. Institute of Chinese Medical Sciences, University of Macau Institute of Chinese Medical Sciences, Macau, Macao

    Jianbo Xiao

  2. School of Pharmacy & Biomolecular Sci., Liverpool John Moores University School of Pharmacy & Biomolecular Sci., Liverpool, UK

    Satyajit D. Sarker

  3. Faculty of Pharmaceutical Sciences, Tokushima Bunri University Faculty of Pharmaceutical Sciences, Tokushima, Japan

    Yoshinori Asakawa

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El-Seedi, H.R. et al. (2020). Dietary Xanthones. In: Xiao, J., Sarker, S., Asakawa, Y. (eds) Handbook of Dietary Phytochemicals. Springer, Singapore. https://doi.org/10.1007/978-981-13-1745-3_11-1

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  • DOI: https://doi.org/10.1007/978-981-13-1745-3_11-1

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  • Print ISBN: 978-981-13-1745-3

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