Encyclopedia of Ionic Liquids

Living Edition
| Editors: Suojiang Zhang

Ionic Liquids for Anticancer Application

  • Maya GunchevaEmail author
Living reference work entry
DOI: https://doi.org/10.1007/978-981-10-6739-6_6-1

Synonyms

Introduction

Cancer is a serious life-threatening and/or chronic disease with a considerable social and economic impact on a global scale. The World Health Organization reports for 18.1 million newly registered cancer patients and 9.6 million cancer deaths in 2018 (https://www.who.int/cancer/PRGlobocanFinal.pdf). While searching for innovative and effective anticancer drugs, researchers have focused their attention on ionic liquids (ILs) as potential anticancer therapeutics. ILs are compounds composed of large organic cations and organic or inorganic anions [1]. In general, they are characterized with low melting points (below 100 °C), low volatility, and high-temperature stability [1]. Their chemical structure can be easily modified; therefore their physicochemical properties and biological activities are easily tunable. ILs are synthesized via reactions of neutralization or metatheses [1].

Cellular toxicity is a complex process involving multiple pathways,...

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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  1. 1.Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of SciencesSofiaBulgaria

Section editors and affiliations

  • Zhonghao Li
    • 1
  • Maya Guncheva
    • 2
  1. 1.Key Laboratory of Colloid and Interface Chemistry, Ministry of EducationShandong UniversityJinanChina
  2. 2.Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of SciencesSofiaBulgaria