Fluorination

Living Edition
| Editors: Jinbo Hu, Teruo Umemoto

Fluoroolefin-Amine Adduct Deoxofluorination

  • Viacheslav Petrov
Living reference work entry
DOI: https://doi.org/10.1007/978-981-10-1855-8_24-1

Fluoroolefin-amine adducts (FAAs) belong to a broader group of α,α-fluoroalkyl amino reagents (FAR). FAAs are widely used for the conversion of alcohols and acids into the corresponding alkyl or acyl fluorides. Fluoroolefin-amine adducts (FAAs) are one of the oldest group of organic fluorinating agents, which became very popular due to their availability, simple synthesis, and ability to convert alcohols and acids into alkyl and acyl fluorides. The application of the first representative of this group – adduct of chlorotrifluoroethylene and diethylamine (Yarovenko reagent) – as a reagent for conversion of alcohols into alkyl fluorides was reported in 1959 [1].

The chemistry of FAAs and FAR was previously overviewed. Detailed reports can be found in the following articles: synthesis and chemistry of Yarovenko reagent [1], Yarovenko and Ishikawa reagents [2], TFEDMA reagent [3], adducts of amines and 2-H-pentafluoropropene [4], and FAR reagents [5].

The synthesis of FAAs is...

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© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  1. 1.FluoroproductsChemours Co.WilmingtonUSA