Supercritical Fluid Extraction: Modifier
Living reference work entry
Expansion of Targeted Hydrophobic Compounds Using a Modifier
As previously described, SC–CO 2 is a suitable medium to extract hydrophobic compounds. On the other hand, complex lipids (e.g., phospholipids, PLs, and glycolipids, GLs) have higher polarity than neutral lipids (e.g., TAG), because they have a hydrophilic head groups (i.e., phosphate groups or sugars). Therefore, extraction efficiencies of complex lipids are lower than that of neutral lipids by SFE with SC–CO 2. However, the polarity of SC–CO 2can be changed considerably by adding a polar organic solvent such as methanol, ethanol, etc., as a modifier. Thus, in recent years, many SFE applications using greener and less toxic...
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