Nanotechnology Applications in Polymerase Chain Reaction (PCR)
Polymerase chain reaction (PCR) is the most prevalent technology used in modern molecular biology research. Generally, it is a technique to amplify the amount of a piece of DNA with a specific sequence. Although the PCR technique is mature, improvement of its efficiency is still an emerging area of research. Recently, nanotechnology is getting more attention in this application. Several nanometer-sized materials such as carbon nanotubes, gold nanoparticles, quantum dots, and metal oxide nanoparticles have been employed.
The polymerase chain reaction (PCR) technique is a series of chemical processes to exponentially amplify the number of a specific DNA sequence, producing hundreds of thousands of copies of DNA from a low original sample concentration. This revolutionary technique was first developed by Dr. Kary Mullis in 1983 . Since then, it has been broadly utilized in medical, biomedical,...
KeywordsPolymerase Chain Reaction TiO2 Nanoparticles Polymerase Chain Reaction Technique Conventional Polymerase Chain Reaction Mercaptoacetic Acid
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