Encyclopedia of Nanotechnology

Living Edition
| Editors: Bharat Bhushan

Surface-Enhanced Raman Scattering for Imaging Biological Cells

  • Nicolas Pavillon
  • Katsumasa Fujita
  • Nicholas SmithEmail author
Living reference work entry
DOI: https://doi.org/10.1007/978-94-007-6178-0_101016-1


Nanoparticles, as a term, generally refer to any type of particle that is composed of metallic, semiconductor, or even biological material. The particles sizes that fall under the term usually range from around 1 to 100 nm in diameter. Very small size nanoparticles, where the number and arrangement of atoms are well determined, are also termed nanoclusters (e.g., a 22-atom gold nanoparticle is usually referred to as a nanocluster). In the current article, the term “nanoparticles” is used to refer to 50 nm diameter gold nanoparticles, unless otherwise noted. Surface-enhanced Raman scattering (SERS) is a term that refers to the amplification of the wavelength shift in scattered light where the shift is caused by vibrations in a sample (similar to a Doppler shift), and the amplification is caused by the presence of a surface. “Biological cells” usually refer to living cells, either in tissue or cultured on a substrate. Whether mammalian or not, cells are the building blocks of...


Gold Nanoparticles SERS Spectrum SERS Signal Plasmonic Property Intracellular Molecule 
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Copyright information

© Springer Science+Business Media Dordrecht 2015

Authors and Affiliations

  • Nicolas Pavillon
    • 1
  • Katsumasa Fujita
    • 2
  • Nicholas Smith
    • 1
    Email author
  1. 1.Biophotonics Lab, Immunology Frontier Research Center (IFReC)Osaka UniversityOsakaJapan
  2. 2.Department of Applied PhysicsOsaka UniversityOsakaJapan