Encyclopedia of Nanotechnology

Living Edition
| Editors: Bharat Bhushan

Optofluidic Resonators and Sensors

  • Zhenyu LiEmail author
Living reference work entry
DOI: https://doi.org/10.1007/978-94-007-6178-0_101012-1



Optofluidic resonators are optical microcavities that are partially or completely made of liquids. Sensors based on optofluidic resonators use either passive cavity resonance shift or active lasing to detect small changes in refractive index, absorption, gain, or scattering in the vicinity of the resonator.


Optofluidics refers to the synergistic fusion of microfluidics and photonics [1, 2]. By integrating photonic and fluidic functions on a single chip, optofluidics not only gives rise to highly compact and integrated microsystems but also enables novel adaptive and reconfigurable photonic devices via microfluidic liquid manipulation. Although both photonics and fluidics have been independently miniaturized within the past three decades, it was not until very recently that the monolithic integration of the two became possible. Today, the channel dimensions in microfluidic devices have become comparable to or even smaller than the...


Resonant Wavelength Liquid Core Whisper Gallery Mode Optical Resonator Microring Resonator 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
This is a preview of subscription content, log in to check access.


  1. 1.
    Psaltis, D., Quake, S.R., Yang, C.: Developing optofluidic technology through the fusion of microfluidics and optics. Nature 442, 381–386 (2006)CrossRefGoogle Scholar
  2. 2.
    Monat, C., Domachuk, P., Eggleton, B.J.: Integrated optofluidics: a new river of light. Nat. Photonics 1, 106–114 (2007)CrossRefGoogle Scholar
  3. 3.
    Vahala, K.: Optical Microcavities. World Scientific, Singapore (2005)CrossRefGoogle Scholar
  4. 4.
    Li, Z.Y., Zhang, Z.Y., Scherer, A., Psaltis, D.: Optofluidic microring dye laser. IEEE/LEOS Summer Topical Meetings, Jul 2007Google Scholar
  5. 5.
    McDonald, J.C., Whitesides, G.M.: Poly(dimethylsiloxane) as a material for fabricating microfluidic devices. Acc. Chem. Res. 35(7), 491–499 (2002)CrossRefGoogle Scholar
  6. 6.
    Vollmer, F., Arnold, S.: Whispering-gallery mode biosensing: label-free detection down to single molecules. Nat. Methods 5(7), 591–596 (2008)CrossRefGoogle Scholar
  7. 7.
    Fan, X., White, I.M.: Optofluidic microsystems for chemical and biological analysis. Nat. Photonics 5, 591–597 (2011)CrossRefGoogle Scholar
  8. 8.
    Bailey, R.: Future Sci. Bioanalysis 1(6), 1043–1047 (2009)CrossRefGoogle Scholar
  9. 9.
    Mandal, S., Goddard, J., Erickson, D.: A multiplexed optofluidic biomolecular sensor for low mass detection. Lab Chip 9, 2924–2932 (2009)CrossRefGoogle Scholar
  10. 10.
    Li, Z.Y., Zhang, Z.Y., Emery, T., Scherer, A., Psaltis, D.: Single mode optofluidic distributed feedback dye laser. Opt. Express 14, 696–701 (2006)CrossRefGoogle Scholar
  11. 11.
    Gather, M.C., Yun, S.H.: Single-cell biological lasers. Nat. Photonics 5, 406–410 (2011)CrossRefGoogle Scholar
  12. 12.
    Li, Z., Psaltis, D.: Optofluidic dye lasers. Microfluid. Nanofluid. 4, 145–158 (2008)CrossRefGoogle Scholar
  13. 13.
    Sun, Y., Fan, X.: Distinguishing DNA by analog-to-digital like conversion by using optofluidic lasers. Angew. Chem. Int. Ed. 51, 1236–1239 (2012)CrossRefGoogle Scholar
  14. 14.
    Fan, X., Yun, S.-H.: The potential of optofluidic biolasers. Nat. Methods 11, 141–147 (2014)CrossRefGoogle Scholar
  15. 15.
    Chen, Q., Ritt, M., Sivaramakrishnan, S., Sun, Y., Fan, X.: Optofluidic lasers with a single molecular layer of gain. Lab. Chip 14, 4590–4595 (2014)CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media Dordrecht 2015

Authors and Affiliations

  1. 1.Department of Biomedical EngineeringThe George Washington UniversityWashingtonUSA