Encyclopedia of Nanotechnology

Living Edition
| Editors: Bharat Bhushan

Nanotechnology in Pulmonary Disease

  • James C. Bonner
Living reference work entry
DOI: https://doi.org/10.1007/978-94-007-6178-0_100904-1

Definition

Nanotechnology in pulmonary disease encompasses the potential human health risks from occupational, environmental, or consumer exposure to engineered nanomaterials as well as the therapeutic benefits of nanomaterials for drug delivery to treat pulmonary diseases, enhance medical imaging of lung diseases, or provide tissue engineering for regenerative medicine.

Introduction

Engineered nanomaterials (ENMs) are intentionally manufactured nanoparticles with at least one dimension <100 nm that can be mass produced with a high degree of conformity in size and shape. The risk of ENMs to human health, specifically pulmonary disease, is not yet known due to the relative infancy of the nanotechnology revolution. However, studies with rodents that show adverse pro-inflammatory, pro-fibrogenic, and carcinogenic effects suggest that at least some ENMs will pose a human health hazard. Also, the utility of ENMs for therapies aimed at the treatment of pulmonary diseases in an early stage of...

Keywords

Chronic Obstructive Pulmonary Disease Pulmonary Fibrosis Solid Lipid Nanoparticles Allergic Airway Inflammation Super Paramagnetic Iron Oxide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Springer Science+Business Media Dordrecht 2014

Authors and Affiliations

  1. 1.Department of Biological SciencesNorth Carolina State UniversityRaleighUSA